Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | DSC1-DSG2 | DSC1_HUMAN - DSG2_HUMAN | Adhesion-Adhesion | Adhesion by Desmosome |
| 2 | DSC2-DSG2 | DSC2_HUMAN - DSG2_HUMAN | Adhesion-Adhesion | Adhesion by Desmosome |
| 3 | DSG1-DSC1 | DSG1_HUMAN - DSC1_HUMAN | Adhesion-Adhesion | Adhesion by Desmosome |
| 4 | DSG1-DSC2 | DSG1_HUMAN - DSC2_HUMAN | Adhesion-Adhesion | Adhesion by Desmosome |
| 5 | DSG1-DSC3 | DSG1_HUMAN - DSC3_HUMAN | Adhesion-Adhesion | Adhesion by Desmosome |
| 6 | DSG2-DSC3 | DSG2_HUMAN - DSC3_HUMAN | Adhesion-Adhesion | Adhesion by Desmosome |
| Name | desmosome |
| ID | GO_0030057 |
| collection_id | Cellular component |
| Exact synonym | macula adherens, spot desmosome |
| Description | A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. |
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| Genes |