Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| keratinocyte | 4 studies | 41% ± 19% |
Insufficient scRNA-seq data for expression of DSG1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 37% | 1045.02 | 540 / 1445 | 52% | 36.80 | 95 / 183 |
| skin | 72% | 42646.48 | 1306 / 1809 | 15% | 10.99 | 71 / 472 |
| liver | 23% | 105.82 | 52 / 226 | 54% | 3.80 | 221 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 17.45 | 27 / 45 |
| uterus | 1% | 146.65 | 2 / 170 | 31% | 8.00 | 140 / 459 |
| breast | 6% | 28.15 | 27 / 459 | 17% | 5.02 | 190 / 1118 |
| lung | 0% | 5.37 | 2 / 578 | 20% | 2.22 | 232 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 15% | 4.64 | 74 / 504 |
| thymus | 0% | 1.85 | 3 / 653 | 4% | 0.80 | 24 / 605 |
| intestine | 0% | 0.98 | 1 / 966 | 4% | 1.89 | 22 / 527 |
| pancreas | 0% | 2.33 | 1 / 328 | 3% | 0.26 | 6 / 178 |
| stomach | 0% | 0 | 0 / 359 | 3% | 0.05 | 8 / 286 |
| adipose | 2% | 64.91 | 24 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 2% | 0.05 | 8 / 430 |
| heart | 2% | 7.14 | 16 / 861 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 1% | 0.01 | 4 / 502 |
| muscle | 1% | 12.17 | 6 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 1.93 | 6 / 2642 | 0% | 0 | 0 / 705 |
| blood vessel | 0% | 31.19 | 3 / 1335 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 1 / 901 |
| peripheral blood | 0% | 0.39 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007043 | Biological process | cell-cell junction assembly |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0050821 | Biological process | protein stabilization |
| GO_0016339 | Biological process | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0032570 | Biological process | response to progesterone |
| GO_0060135 | Biological process | maternal process involved in female pregnancy |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
| GO_0001533 | Cellular component | cornified envelope |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0005829 | Cellular component | cytosol |
| GO_0016328 | Cellular component | lateral plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
| GO_0030057 | Cellular component | desmosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0015643 | Molecular function | toxic substance binding |
| GO_0045295 | Molecular function | gamma-catenin binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DSG1 |
| Protein name | Desmoglein type 1 Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen) |
| Synonyms | CDHF4 |
| Description | FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Accessions | Q02413 Q712V6 ENST00000257192.5 [Q02413-1] |