DSG1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DSG1 at tissue level.

III. Associated gene sets

GO_0007043Biological processcell-cell junction assembly
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0050821Biological processprotein stabilization
GO_0016339Biological processcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0098609Biological processcell-cell adhesion
GO_0032570Biological processresponse to progesterone
GO_0060135Biological processmaternal process involved in female pregnancy
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0001533Cellular componentcornified envelope
GO_0005911Cellular componentcell-cell junction
GO_0005829Cellular componentcytosol
GO_0016328Cellular componentlateral plasma membrane
GO_0005737Cellular componentcytoplasm
GO_0101003Cellular componentficolin-1-rich granule membrane
GO_0030057Cellular componentdesmosome
GO_0005634Cellular componentnucleus
GO_0015643Molecular functiontoxic substance binding
GO_0045295Molecular functiongamma-catenin binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDSG1
Protein nameDesmoglein type 1
Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)
SynonymsCDHF4
DescriptionFUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

AccessionsQ02413
Q712V6
ENST00000257192.5 [Q02413-1]