Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 5 studies | 29% ± 7% | |
| keratinocyte | 5 studies | 32% ± 14% | |
| epithelial cell | 3 studies | 27% ± 14% |
Insufficient scRNA-seq data for expression of DSG3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 40% | 27989.92 | 574 / 1445 | 68% | 346.76 | 124 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 424.96 | 43 / 45 |
| skin | 72% | 6738.24 | 1309 / 1809 | 8% | 7.09 | 36 / 472 |
| uterus | 2% | 681.69 | 3 / 170 | 54% | 233.54 | 249 / 459 |
| breast | 37% | 622.65 | 170 / 459 | 14% | 17.39 | 161 / 1118 |
| lung | 0% | 0 | 0 / 578 | 39% | 106.51 | 453 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 22% | 48.27 | 109 / 504 |
| intestine | 3% | 28.70 | 28 / 966 | 15% | 17.05 | 78 / 527 |
| pancreas | 0% | 6.97 | 1 / 328 | 16% | 13.08 | 28 / 178 |
| stomach | 1% | 65.76 | 2 / 359 | 12% | 7.47 | 34 / 286 |
| thymus | 0% | 3.29 | 2 / 653 | 5% | 4.29 | 28 / 605 |
| prostate | 4% | 42.34 | 9 / 245 | 0% | 0 | 0 / 502 |
| adipose | 2% | 44.60 | 21 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 7.08 | 2 / 803 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0.05 | 1 / 430 |
| blood vessel | 0% | 3.57 | 3 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| brain | 0% | 0 | 0 / 2642 | 0% | 0 | 0 / 705 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0 | 0 / 901 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0001533 | Cellular component | cornified envelope |
| GO_0030057 | Cellular component | desmosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DSG3 |
| Protein name | Desmoglein-3 (130 kDa pemphigus vulgaris antigen) (PVA) (Cadherin family member 6) |
| Synonyms | CDHF6 |
| Description | FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Accessions | ENST00000257189.5 P32926 |