Insufficient scRNA-seq data for expression of DSG4 at single-cell level.
Insufficient scRNA-seq data for expression of DSG4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 65% | 302.95 | 1168 / 1809 | 0% | 0.03 | 2 / 472 |
esophagus | 39% | 30.04 | 558 / 1445 | 11% | 0.24 | 21 / 183 |
intestine | 16% | 2.33 | 152 / 966 | 24% | 0.42 | 126 / 527 |
breast | 32% | 5.23 | 149 / 459 | 0% | 0.01 | 4 / 1118 |
bladder | 19% | 2.33 | 4 / 21 | 12% | 0.61 | 59 / 504 |
stomach | 17% | 2.81 | 62 / 359 | 13% | 0.27 | 36 / 286 |
adipose | 28% | 16.63 | 340 / 1204 | 0% | 0 | 0 / 0 |
prostate | 18% | 9.83 | 43 / 245 | 1% | 0.02 | 7 / 502 |
liver | 14% | 1.78 | 31 / 226 | 0% | 0.01 | 2 / 406 |
uterus | 2% | 1.01 | 3 / 170 | 8% | 0.59 | 37 / 459 |
lung | 1% | 0.09 | 4 / 578 | 5% | 0.28 | 62 / 1155 |
pancreas | 0% | 0.02 | 1 / 328 | 3% | 0.10 | 6 / 178 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
peripheral blood | 2% | 0.33 | 18 / 929 | 0% | 0 | 0 / 0 |
muscle | 1% | 0.10 | 5 / 803 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 180 | 0% | 0.01 | 2 / 430 |
spleen | 0% | 0.07 | 1 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 0.03 | 1 / 258 | 0% | 0 | 0 / 230 |
brain | 0% | 0.07 | 10 / 2642 | 0% | 0 | 0 / 705 |
heart | 0% | 0.03 | 3 / 861 | 0% | 0 | 0 / 0 |
thymus | 0% | 0.03 | 2 / 653 | 0% | 0 | 0 / 605 |
kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 2 / 901 |
blood vessel | 0% | 0.01 | 2 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030509 | Biological process | BMP signaling pathway |
GO_0030216 | Biological process | keratinocyte differentiation |
GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0001942 | Biological process | hair follicle development |
GO_0001533 | Cellular component | cornified envelope |
GO_0030057 | Cellular component | desmosome |
GO_0005886 | Cellular component | plasma membrane |
GO_0005509 | Molecular function | calcium ion binding |
Gene name | DSG4 |
Protein name | Desmoglein-4 (Cadherin family member 13) |
Synonyms | CDHF13 |
Description | FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). . |
Accessions | ENST00000308128.9 [Q86SJ6-1] ENST00000359747.4 [Q86SJ6-2] Q86SJ6 |