DSG4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DSG4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DSG4 at tissue level.

III. Associated gene sets

GO_0030509Biological processBMP signaling pathway
GO_0030216Biological processkeratinocyte differentiation
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0098609Biological processcell-cell adhesion
GO_0001942Biological processhair follicle development
GO_0001533Cellular componentcornified envelope
GO_0030057Cellular componentdesmosome
GO_0005886Cellular componentplasma membrane
GO_0005509Molecular functioncalcium ion binding

IV. Literature review

[source]
Gene nameDSG4
Protein nameDesmoglein-4 (Cadherin family member 13)
SynonymsCDHF13
DescriptionFUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). .

AccessionsENST00000308128.9 [Q86SJ6-1]
ENST00000359747.4 [Q86SJ6-2]
Q86SJ6