DSC1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DSC1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DSC1 at tissue level.

III. Associated gene sets

GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0098609Biological processcell-cell adhesion
GO_0001533Cellular componentcornified envelope
GO_0030057Cellular componentdesmosome
GO_0101003Cellular componentficolin-1-rich granule membrane
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005921Cellular componentgap junction
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDSC1
Protein nameDesmocollin 1, isoform CRA_b (Desmocollin 1b)
Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3)
SynonymsCDHF1
hCG_25474
DescriptionFUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues.

AccessionsQ9HB00
Q08554
ENST00000257197.7 [Q08554-2]
ENST00000257198.6 [Q08554-1]