Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 5 studies | 31% ± 19% | |
squamous epithelial cell | 4 studies | 46% ± 20% | |
basal cell | 3 studies | 35% ± 15% |
Insufficient scRNA-seq data for expression of EVPL at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 82% | 3369.61 | 538 / 653 | 84% | 51.70 | 511 / 605 |
lung | 54% | 2283.44 | 311 / 578 | 92% | 52.13 | 1058 / 1155 |
prostate | 48% | 1961.87 | 117 / 245 | 98% | 31.96 | 490 / 502 |
intestine | 42% | 1677.08 | 409 / 966 | 94% | 56.22 | 496 / 527 |
esophagus | 39% | 23786.40 | 564 / 1445 | 97% | 111.34 | 177 / 183 |
bladder | 38% | 3354.86 | 8 / 21 | 94% | 104.40 | 473 / 504 |
ureter | 0% | 0 | 0 / 0 | 100% | 199.85 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 96% | 85.56 | 43 / 45 |
breast | 5% | 141.26 | 21 / 459 | 88% | 27.29 | 989 / 1118 |
stomach | 3% | 117.18 | 9 / 359 | 89% | 47.30 | 254 / 286 |
pancreas | 0% | 8.45 | 1 / 328 | 87% | 45.47 | 154 / 178 |
uterus | 2% | 477.11 | 4 / 170 | 83% | 77.05 | 383 / 459 |
ovary | 0% | 0 | 0 / 180 | 83% | 24.55 | 359 / 430 |
skin | 72% | 29227.15 | 1303 / 1809 | 10% | 5.40 | 47 / 472 |
kidney | 43% | 1838.06 | 38 / 89 | 38% | 12.40 | 344 / 901 |
liver | 0% | 0 | 0 / 226 | 9% | 2.58 | 36 / 406 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.44 | 1 / 29 |
adrenal gland | 0% | 0 | 0 / 258 | 1% | 0.25 | 3 / 230 |
adipose | 0% | 35.73 | 6 / 1204 | 0% | 0 | 0 / 0 |
muscle | 0% | 12.52 | 2 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 11.91 | 1 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
brain | 0% | 0 | 0 / 2642 | 0% | 0 | 0 / 705 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0030216 | Biological process | keratinocyte differentiation |
GO_0002786 | Biological process | regulation of antibacterial peptide production |
GO_0031424 | Biological process | keratinization |
GO_0018149 | Biological process | peptide cross-linking |
GO_0008544 | Biological process | epidermis development |
GO_0045104 | Biological process | intermediate filament cytoskeleton organization |
GO_0042060 | Biological process | wound healing |
GO_0001533 | Cellular component | cornified envelope |
GO_0005882 | Cellular component | intermediate filament |
GO_0045111 | Cellular component | intermediate filament cytoskeleton |
GO_0030057 | Cellular component | desmosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0045296 | Molecular function | cadherin binding |
GO_0005198 | Molecular function | structural molecule activity |
Gene name | EVPL |
Protein name | Envoplakin (210 kDa cornified envelope precursor protein) (210 kDa paraneoplastic pemphigus antigen) (p210) Envoplakin EVPL protein |
Synonyms | |
Description | FUNCTION: Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. |
Accessions | K7EQ87 B7ZLH8 ENST00000589231.1 ENST00000586740.1 K7EKI0 Q92817 ENST00000301607.8 |