Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 10 studies | 24% ± 5% | |
basal cell | 10 studies | 32% ± 17% | |
ciliated cell | 9 studies | 21% ± 6% | |
epithelial cell | 6 studies | 45% ± 18% | |
respiratory goblet cell | 5 studies | 30% ± 10% | |
club cell | 5 studies | 24% ± 7% | |
squamous epithelial cell | 4 studies | 75% ± 14% | |
hillock cell | 3 studies | 29% ± 10% | |
ionocyte | 3 studies | 20% ± 6% | |
secretory cell | 3 studies | 33% ± 15% | |
glutamatergic neuron | 3 studies | 25% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 93% | 7206.16 | 609 / 653 | 90% | 136.69 | 542 / 605 |
esophagus | 84% | 75366.70 | 1221 / 1445 | 95% | 201.93 | 174 / 183 |
breast | 95% | 13238.63 | 434 / 459 | 83% | 33.77 | 928 / 1118 |
prostate | 73% | 5005.79 | 180 / 245 | 95% | 45.38 | 475 / 502 |
lung | 70% | 5471.14 | 405 / 578 | 90% | 64.94 | 1041 / 1155 |
bladder | 76% | 6155.90 | 16 / 21 | 82% | 56.42 | 412 / 504 |
uterus | 26% | 3015.87 | 44 / 170 | 86% | 104.31 | 393 / 459 |
skin | 87% | 38881.47 | 1570 / 1809 | 20% | 11.70 | 96 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 68.22 | 1 / 1 |
intestine | 30% | 1817.25 | 291 / 966 | 69% | 33.70 | 365 / 527 |
pancreas | 3% | 178.56 | 10 / 328 | 93% | 73.49 | 166 / 178 |
tonsil | 0% | 0 | 0 / 0 | 96% | 165.42 | 43 / 45 |
ovary | 6% | 301.27 | 11 / 180 | 87% | 47.96 | 374 / 430 |
stomach | 19% | 1372.24 | 70 / 359 | 67% | 23.45 | 191 / 286 |
adipose | 81% | 12320.98 | 977 / 1204 | 0% | 0 | 0 / 0 |
kidney | 20% | 969.37 | 18 / 89 | 55% | 23.39 | 500 / 901 |
liver | 7% | 319.31 | 16 / 226 | 28% | 9.89 | 115 / 406 |
blood vessel | 25% | 1569.03 | 331 / 1335 | 0% | 0 | 0 / 0 |
muscle | 17% | 962.14 | 134 / 803 | 0% | 0 | 0 / 0 |
adrenal gland | 4% | 179.81 | 10 / 258 | 10% | 3.99 | 23 / 230 |
brain | 4% | 182.60 | 102 / 2642 | 9% | 2.01 | 60 / 705 |
heart | 1% | 64.41 | 11 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 4.40 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0009612 | Biological process | response to mechanical stimulus |
GO_0031424 | Biological process | keratinization |
GO_0045104 | Biological process | intermediate filament cytoskeleton organization |
GO_0042060 | Biological process | wound healing |
GO_0001533 | Cellular component | cornified envelope |
GO_0005882 | Cellular component | intermediate filament |
GO_0030057 | Cellular component | desmosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0045296 | Molecular function | cadherin binding |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_0005515 | Molecular function | protein binding |
GO_0005198 | Molecular function | structural molecule activity |
Gene name | PPL |
Protein name | Periplakin Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein) |
Synonyms | KIAA0568 |
Description | FUNCTION: Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling. . |
Accessions | ENST00000590782.6 K7EQ71 ENST00000592772.1 K7EKI8 ENST00000345988.7 O60437 |