PPL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009612Biological processresponse to mechanical stimulus
GO_0031424Biological processkeratinization
GO_0045104Biological processintermediate filament cytoskeleton organization
GO_0042060Biological processwound healing
GO_0001533Cellular componentcornified envelope
GO_0005882Cellular componentintermediate filament
GO_0030057Cellular componentdesmosome
GO_0070062Cellular componentextracellular exosome
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0045296Molecular functioncadherin binding
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0005515Molecular functionprotein binding
GO_0005198Molecular functionstructural molecule activity

IV. Literature review

[source]
Gene namePPL
Protein namePeriplakin
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
SynonymsKIAA0568
DescriptionFUNCTION: Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling. .

AccessionsENST00000590782.6
K7EQ71
ENST00000592772.1
K7EKI8
ENST00000345988.7
O60437