KRT8 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
epithelial cell	22 studies	80% ± 17%	Explore
basal cell	20 studies	68% ± 20%	Explore
ciliated cell	18 studies	70% ± 20%	Explore
secretory cell	11 studies	78% ± 14%	Explore
goblet cell	11 studies	83% ± 17%	Explore
mesothelial cell	11 studies	76% ± 23%	Explore
type I pneumocyte	10 studies	66% ± 24%	Explore
club cell	10 studies	62% ± 27%	Explore
type II pneumocyte	9 studies	59% ± 22%	Explore
fibroblast	9 studies	27% ± 13%	Explore
respiratory goblet cell	8 studies	67% ± 25%	Explore
enterocyte	8 studies	87% ± 16%	Explore
brush cell	8 studies	80% ± 24%	Explore
ionocyte	7 studies	82% ± 17%	Explore
epithelial cell of proximal tubule	7 studies	37% ± 16%	Explore
abnormal cell	7 studies	51% ± 26%	Explore
progenitor cell	7 studies	84% ± 27%	Explore
smooth muscle cell	7 studies	35% ± 18%	Explore
kidney loop of Henle epithelial cell	6 studies	41% ± 14%	Explore
enteroendocrine cell	6 studies	62% ± 30%	Explore
duct epithelial cell	5 studies	73% ± 27%	Explore
renal alpha-intercalated cell	5 studies	71% ± 5%	Explore
neuroendocrine cell	5 studies	84% ± 20%	Explore
mucus secreting cell	5 studies	56% ± 16%	Explore
deuterosomal cell	4 studies	55% ± 16%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	43% ± 11%	Explore
intestinal crypt stem cell	4 studies	93% ± 7%	Explore
transit amplifying cell	4 studies	89% ± 12%	Explore
connective tissue cell	4 studies	35% ± 12%	Explore
endothelial cell	4 studies	23% ± 6%	Explore
acinar cell	4 studies	57% ± 25%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	89% ± 7%	Explore
luminal cell of prostate epithelium	4 studies	61% ± 18%	Explore
hillock cell	3 studies	61% ± 25%	Explore
squamous epithelial cell	3 studies	49% ± 27%	Explore
pancreatic A cell	3 studies	57% ± 24%	Explore
type B pancreatic cell	3 studies	47% ± 21%	Explore
T cell	3 studies	44% ± 26%	Explore
pericyte	3 studies	21% ± 4%	Explore
paneth cell	3 studies	77% ± 17%	Explore
renal principal cell	3 studies	74% ± 8%	Explore
extravillous trophoblast	3 studies	100% ± 0%	Explore
placental villous trophoblast	3 studies	98% ± 1%	Explore
serous secreting cell	3 studies	60% ± 11%	Explore
myoepithelial cell	3 studies	85% ± 2%	Explore
cholangiocyte	3 studies	44% ± 28%	Explore
pancreatic ductal cell	3 studies	90% ± 3%	Explore
hepatocyte	3 studies	36% ± 5%	Explore
progenitor cell of mammary luminal epithelium	3 studies	66% ± 33%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	40% ± 21%	Explore
intestine	10 studies	47% ± 26%	Explore
kidney	6 studies	26% ± 9%	Explore
prostate	5 studies	52% ± 21%	Explore
pancreas	4 studies	55% ± 21%	Explore
breast	4 studies	36% ± 17%	Explore
placenta	3 studies	73% ± 28%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	33142.18	328 / 328	97%	923.48	172 / 178
thymus	100%	23076.38	653 / 653	96%	409.23	582 / 605
prostate	94%	14478.60	230 / 245	99%	407.30	496 / 502
stomach	94%	30390.69	338 / 359	97%	1037.96	278 / 286
lung	97%	15988.69	558 / 578	92%	522.24	1064 / 1155
liver	100%	22293.27	225 / 226	87%	375.64	352 / 406
kidney	100%	19675.34	89 / 89	81%	307.05	729 / 901
intestine	81%	51328.16	779 / 966	98%	1249.57	516 / 527
bladder	81%	13281.14	17 / 21	93%	948.65	470 / 504
breast	60%	12717.75	275 / 459	95%	687.55	1065 / 1118
esophagus	82%	9628.65	1184 / 1445	72%	466.81	131 / 183
ovary	9%	375.17	16 / 180	99%	610.83	426 / 430
uterus	28%	1360.08	48 / 170	74%	537.51	339 / 459
ureter	0%	0	0 / 0	100%	1332.25	1 / 1
heart	85%	7204.82	732 / 861	0%	0	0 / 0
adrenal gland	69%	3268.40	178 / 258	3%	6.72	8 / 230
tonsil	0%	0	0 / 0	69%	261.04	31 / 45
skin	41%	2416.67	736 / 1809	0%	0	0 / 472
blood vessel	37%	2515.60	495 / 1335	0%	0	0 / 0
adipose	35%	5278.14	420 / 1204	0%	0	0 / 0
spleen	12%	458.23	30 / 241	0%	0	0 / 0
peripheral blood	1%	127.84	13 / 929	0%	0	0 / 0
brain	0%	4.15	3 / 2642	0%	0.18	1 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0097191	Biological process	extrinsic apoptotic signaling pathway
GO_0051599	Biological process	response to hydrostatic pressure
GO_0051707	Biological process	response to other organism
GO_0097284	Biological process	hepatocyte apoptotic process
GO_0060706	Biological process	cell differentiation involved in embryonic placenta development
GO_0045214	Biological process	sarcomere organization
GO_0033209	Biological process	tumor necrosis factor-mediated signaling pathway
GO_0043034	Cellular component	costamere
GO_0030018	Cellular component	Z disc
GO_0042383	Cellular component	sarcolemma
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0016010	Cellular component	dystrophin-associated glycoprotein complex
GO_0005882	Cellular component	intermediate filament
GO_0005911	Cellular component	cell-cell junction
GO_0016363	Cellular component	nuclear matrix
GO_0045111	Cellular component	intermediate filament cytoskeleton
GO_0005829	Cellular component	cytosol
GO_0045095	Cellular component	keratin filament
GO_0005737	Cellular component	cytoplasm
GO_0016327	Cellular component	apicolateral plasma membrane
GO_0005634	Cellular component	nucleus
GO_0044877	Molecular function	protein-containing complex binding
GO_0097110	Molecular function	scaffold protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	KRT8
Protein name	Keratin 8 Keratin, type II cytoskeletal 8 (Cytokeratin-8) (Keratin-8) (Type-II keratin Kb8) Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Synonyms	CYK8
Description	FUNCTION: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. . FUNCTION: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. . FUNCTION: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. . FUNCTION: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. . FUNCTION: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. .
Accessions	ENST00000552150.5 [P05787-2] ENST00000619952.2 F8VP67 ENST00000546826.5 F8W1U3 ENST00000548998.5 H0YIB2 ENST00000293308.11 [P05787-1] Q969I0 ENST00000546542.1 ENST00000546900.1 ENST00000546897.5 [P05787-1] ENST00000547176.3 ENST00000552551.5 [P05787-1] F8VQY3 A0A0U1RQU6 F8VUG2 ENST00000692008.1 [P05787-1] P05787

KRT8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review