dystrophin-associated glycoprotein complex

I. Literature review

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Namedystrophin-associated glycoprotein complex
IDGO_0016010
collection_id

Cellular component

Exact synonym

DGC, dystrophin glycoprotein complex

Description

A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.

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Genes