I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 13 studies | 37% ± 16% | |
| cardiac muscle cell | 5 studies | 25% ± 3% | |
| pericyte | 4 studies | 20% ± 1% | |
| glutamatergic neuron | 3 studies | 33% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 13 studies | 37% ± 16% | |
| cardiac muscle cell | 5 studies | 25% ± 3% | |
| pericyte | 4 studies | 20% ± 1% | |
| glutamatergic neuron | 3 studies | 33% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 23% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 9435.80 | 653 / 653 | 99% | 153.81 | 598 / 605 |
| brain | 97% | 8915.01 | 2573 / 2642 | 99% | 140.81 | 697 / 705 |
| breast | 94% | 2816.19 | 430 / 459 | 93% | 34.21 | 1040 / 1118 |
| prostate | 87% | 2185.16 | 213 / 245 | 100% | 64.23 | 500 / 502 |
| ovary | 89% | 2068.37 | 161 / 180 | 96% | 41.03 | 412 / 430 |
| adrenal gland | 84% | 1810.78 | 217 / 258 | 98% | 71.07 | 226 / 230 |
| uterus | 88% | 1988.14 | 150 / 170 | 94% | 44.42 | 432 / 459 |
| kidney | 83% | 1950.40 | 74 / 89 | 98% | 62.27 | 885 / 901 |
| bladder | 95% | 4218.57 | 20 / 21 | 80% | 28.32 | 404 / 504 |
| esophagus | 73% | 1868.78 | 1061 / 1445 | 67% | 17.43 | 122 / 183 |
| skin | 44% | 819.48 | 799 / 1809 | 94% | 56.59 | 446 / 472 |
| stomach | 76% | 1920.64 | 272 / 359 | 59% | 19.29 | 168 / 286 |
| intestine | 71% | 1738.88 | 682 / 966 | 57% | 13.58 | 299 / 527 |
| liver | 23% | 347.38 | 51 / 226 | 94% | 38.81 | 381 / 406 |
| lung | 19% | 293.19 | 107 / 578 | 87% | 33.59 | 1010 / 1155 |
| eye | 0% | 0 | 0 / 0 | 100% | 188.50 | 80 / 80 |
| muscle | 100% | 13977.58 | 803 / 803 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 61.62 | 1 / 1 |
| blood vessel | 100% | 6651.28 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 11720.47 | 855 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 13% | 189.26 | 41 / 328 | 85% | 23.59 | 152 / 178 |
| adipose | 95% | 3645.12 | 1143 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 39.45 | 42 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 28.68 | 18 / 29 |
| spleen | 2% | 30.83 | 5 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 27.84 | 12 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0060307 | Biological process | regulation of ventricular cardiac muscle cell membrane repolarization |
| GO_0086005 | Biological process | ventricular cardiac muscle cell action potential |
| GO_0002027 | Biological process | regulation of heart rate |
| GO_0006936 | Biological process | muscle contraction |
| GO_0007528 | Biological process | neuromuscular junction development |
| GO_1902083 | Biological process | negative regulation of peptidyl-cysteine S-nitrosylation |
| GO_0003117 | Biological process | regulation of vasoconstriction by circulating norepinephrine |
| GO_1902305 | Biological process | regulation of sodium ion transmembrane transport |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005622 | Cellular component | intracellular anatomical structure |
| GO_0016013 | Cellular component | syntrophin complex |
| GO_0031594 | Cellular component | neuromuscular junction |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0016010 | Cellular component | dystrophin-associated glycoprotein complex |
| GO_0070161 | Cellular component | anchoring junction |
| GO_0016328 | Cellular component | lateral plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0050998 | Molecular function | nitric-oxide synthase binding |
| GO_0005198 | Molecular function | structural molecule activity |
| GO_0030165 | Molecular function | PDZ domain binding |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0051117 | Molecular function | ATPase binding |
| GO_0005516 | Molecular function | calmodulin binding |
| GO_0017080 | Molecular function | sodium channel regulator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003779 | Molecular function | actin binding |
| Gene name | SNTA1 |
| Protein name | Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1) Syntrophin, alpha 1 (Dystrophin-associated protein A1, 59kDa, acidic component), isoform CRA_a (cDNA FLJ38623 fis, clone HEART2008509, highly similar to Alpha-1-syntrophin) SNTA1 protein |
| Synonyms | hCG_37901 SNT1 |
| Description | FUNCTION: Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity). . |
| Accessions | ENST00000217381.3 [Q13424-1] B3KTR0 Q29RY0 Q13424 |
