Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 11 studies | 43% ± 23% | |
intestine | 10 studies | 41% ± 26% | |
kidney | 7 studies | 26% ± 9% | |
pancreas | 4 studies | 46% ± 15% | |
prostate | 4 studies | 62% ± 14% | |
breast | 4 studies | 38% ± 15% | |
placenta | 3 studies | 80% ± 21% | |
esophagus | 3 studies | 30% ± 11% | |
liver | 3 studies | 27% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 18143.23 | 226 / 226 | 98% | 607.88 | 399 / 406 |
pancreas | 100% | 20110.34 | 328 / 328 | 97% | 813.17 | 172 / 178 |
prostate | 93% | 11885.37 | 228 / 245 | 99% | 729.17 | 498 / 502 |
kidney | 100% | 13425.96 | 89 / 89 | 92% | 415.93 | 828 / 901 |
thymus | 100% | 13120.68 | 653 / 653 | 90% | 451.89 | 544 / 605 |
lung | 98% | 11888.15 | 567 / 578 | 89% | 513.55 | 1033 / 1155 |
stomach | 77% | 11661.96 | 275 / 359 | 97% | 932.25 | 277 / 286 |
bladder | 62% | 5002.95 | 13 / 21 | 94% | 985.30 | 475 / 504 |
breast | 61% | 7816.84 | 280 / 459 | 94% | 775.16 | 1055 / 1118 |
intestine | 53% | 10285.14 | 515 / 966 | 98% | 1211.00 | 516 / 527 |
ovary | 19% | 564.87 | 34 / 180 | 99% | 672.72 | 425 / 430 |
esophagus | 46% | 2571.02 | 659 / 1445 | 69% | 362.18 | 127 / 183 |
uterus | 21% | 804.08 | 36 / 170 | 81% | 577.45 | 371 / 459 |
ureter | 0% | 0 | 0 / 0 | 100% | 1091.45 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 78% | 197.31 | 35 / 45 |
spleen | 61% | 1473.49 | 146 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 50% | 1306.69 | 130 / 258 | 4% | 8.31 | 10 / 230 |
skin | 46% | 1636.75 | 834 / 1809 | 4% | 7.08 | 19 / 472 |
adipose | 41% | 4878.09 | 494 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 33% | 1223.36 | 437 / 1335 | 0% | 0 | 0 / 0 |
heart | 23% | 674.41 | 199 / 861 | 0% | 0 | 0 / 0 |
brain | 4% | 72.20 | 98 / 2642 | 0% | 0.18 | 1 / 705 |
peripheral blood | 2% | 131.07 | 16 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 1.58 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0097191 | Biological process | extrinsic apoptotic signaling pathway |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0045104 | Biological process | intermediate filament cytoskeleton organization |
GO_0097284 | Biological process | hepatocyte apoptotic process |
GO_0009653 | Biological process | anatomical structure morphogenesis |
GO_0043001 | Biological process | Golgi to plasma membrane protein transport |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0033209 | Biological process | tumor necrosis factor-mediated signaling pathway |
GO_0005730 | Cellular component | nucleolus |
GO_0005856 | Cellular component | cytoskeleton |
GO_0034451 | Cellular component | centriolar satellite |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005815 | Cellular component | microtubule organizing center |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005882 | Cellular component | intermediate filament |
GO_0016363 | Cellular component | nuclear matrix |
GO_0005829 | Cellular component | cytosol |
GO_0071944 | Cellular component | cell periphery |
GO_0005912 | Cellular component | adherens junction |
GO_0045095 | Cellular component | keratin filament |
GO_0005737 | Cellular component | cytoplasm |
GO_0005198 | Molecular function | structural molecule activity |
GO_0097110 | Molecular function | scaffold protein binding |
GO_0098641 | Molecular function | cadherin binding involved in cell-cell adhesion |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | KRT18 |
Protein name | KRT18 protein Keratin 18 Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18) |
Synonyms | PIG46 CYK18 |
Description | FUNCTION: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. . |
Accessions | F8VZY9 ENST00000388835.4 ENST00000550600.5 I6L965 ENST00000388837.6 P05783 |