Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 9 studies | 42% ± 16% | |
| retinal ganglion cell | 8 studies | 77% ± 27% | |
| endothelial cell | 6 studies | 26% ± 12% | |
| neuron | 5 studies | 49% ± 21% | |
| OFF-bipolar cell | 3 studies | 70% ± 25% | |
| ON-bipolar cell | 3 studies | 67% ± 26% | |
| GABAergic neuron | 3 studies | 41% ± 11% | |
| astrocyte | 3 studies | 37% ± 28% | |
| interneuron | 3 studies | 22% ± 3% | |
| oligodendrocyte | 3 studies | 21% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 7 studies | 31% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 96% | 18506.96 | 2546 / 2642 | 67% | 79.96 | 475 / 705 |
| adrenal gland | 11% | 253.38 | 29 / 258 | 87% | 124.32 | 200 / 230 |
| kidney | 11% | 176.35 | 10 / 89 | 69% | 75.72 | 618 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 33.56 | 23 / 45 |
| esophagus | 15% | 174.42 | 216 / 1445 | 36% | 24.82 | 65 / 183 |
| intestine | 41% | 471.45 | 392 / 966 | 3% | 0.90 | 18 / 527 |
| uterus | 2% | 25.70 | 3 / 170 | 31% | 21.70 | 140 / 459 |
| skin | 12% | 205.98 | 221 / 1809 | 13% | 12.13 | 61 / 472 |
| lung | 0% | 0 | 0 / 578 | 19% | 9.39 | 217 / 1155 |
| prostate | 4% | 72.66 | 11 / 245 | 13% | 2.77 | 67 / 502 |
| stomach | 7% | 58.53 | 24 / 359 | 2% | 1.67 | 7 / 286 |
| thymus | 0% | 3.78 | 1 / 653 | 9% | 17.53 | 54 / 605 |
| pancreas | 0% | 0 | 0 / 328 | 8% | 1.55 | 14 / 178 |
| bladder | 0% | 0 | 0 / 21 | 6% | 8.37 | 32 / 504 |
| ovary | 2% | 23.48 | 3 / 180 | 2% | 0.53 | 8 / 430 |
| liver | 0% | 0 | 0 / 226 | 3% | 1.45 | 14 / 406 |
| breast | 0% | 1.46 | 1 / 459 | 2% | 0.29 | 20 / 1118 |
| eye | 0% | 0 | 0 / 0 | 1% | 3.82 | 1 / 80 |
| heart | 0% | 4.34 | 4 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 1.04 | 2 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0.49 | 1 / 1204 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0021766 | Biological process | hippocampus development |
| GO_0050772 | Biological process | positive regulation of axonogenesis |
| GO_0043434 | Biological process | response to peptide hormone |
| GO_0060052 | Biological process | neurofilament cytoskeleton organization |
| GO_0021510 | Biological process | spinal cord development |
| GO_0008090 | Biological process | retrograde axonal transport |
| GO_0045105 | Biological process | intermediate filament polymerization or depolymerization |
| GO_0008089 | Biological process | anterograde axonal transport |
| GO_1903937 | Biological process | response to acrylamide |
| GO_0050885 | Biological process | neuromuscular process controlling balance |
| GO_0040011 | Biological process | locomotion |
| GO_0014012 | Biological process | peripheral nervous system axon regeneration |
| GO_0007409 | Biological process | axonogenesis |
| GO_1903935 | Biological process | response to sodium arsenite |
| GO_0045109 | Biological process | intermediate filament organization |
| GO_0051258 | Biological process | protein polymerization |
| GO_0033693 | Biological process | neurofilament bundle assembly |
| GO_0000226 | Biological process | microtubule cytoskeleton organization |
| GO_2000672 | Biological process | negative regulation of motor neuron apoptotic process |
| GO_0031133 | Biological process | regulation of axon diameter |
| GO_0097049 | Biological process | motor neuron apoptotic process |
| GO_0099170 | Biological process | postsynaptic modulation of chemical synaptic transmission |
| GO_0021987 | Biological process | cerebral cortex development |
| GO_0009636 | Biological process | response to toxic substance |
| GO_0019896 | Biological process | axonal transport of mitochondrion |
| GO_0099185 | Biological process | postsynaptic intermediate filament cytoskeleton organization |
| GO_0051412 | Biological process | response to corticosterone |
| GO_0090128 | Biological process | regulation of synapse maturation |
| GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
| GO_0031594 | Cellular component | neuromuscular junction |
| GO_0005883 | Cellular component | neurofilament |
| GO_0099160 | Cellular component | postsynaptic intermediate filament cytoskeleton |
| GO_0005882 | Cellular component | intermediate filament |
| GO_0098981 | Cellular component | cholinergic synapse |
| GO_0005829 | Cellular component | cytosol |
| GO_0099182 | Cellular component | presynaptic intermediate filament cytoskeleton |
| GO_0030426 | Cellular component | growth cone |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030424 | Cellular component | axon |
| GO_1904115 | Cellular component | axon cytoplasm |
| GO_0019904 | Molecular function | protein domain specific binding |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0005200 | Molecular function | structural constituent of cytoskeleton |
| GO_0099184 | Molecular function | structural constituent of postsynaptic intermediate filament cytoskeleton |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
| GO_0043274 | Molecular function | phospholipase binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NEFL |
| Protein name | Neurofilament light polypeptide isoform 2 Neurofilament light polypeptide isoform 1 NEFL protein Neurofilament-light Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein) |
| Synonyms | NFL NF68 |
| Description | FUNCTION: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). . |
| Accessions | I6L9F6 A0A0S2Z436 Q7Z5R4 ENST00000610854.2 A0A0S2Z4B1 P07196 |
