MNS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007288Biological processsperm axoneme assembly
GO_0051321Biological processmeiotic cell cycle
GO_0070986Biological processleft/right axis specification
GO_0045724Biological processpositive regulation of cilium assembly
GO_0044782Biological processcilium organization
GO_0005930Cellular componentaxoneme
GO_0160111Cellular componentaxonemal A tubule inner sheath
GO_0005879Cellular componentaxonemal microtubule
GO_0031514Cellular componentmotile cilium
GO_0036126Cellular componentsperm flagellum
GO_0005635Cellular componentnuclear envelope
GO_0005882Cellular componentintermediate filament
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMNS1
Protein nameMeiosis-specific nuclear structural protein 1
SynonymshCG_40113
DescriptionFUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating . May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly (By similarity). May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules . .

AccessionsENST00000260453.4
B3KQ70
Q8NEH6