Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| neuron | 8 studies | 40% ± 18% | |
| retinal ganglion cell | 8 studies | 76% ± 28% | |
| glutamatergic neuron | 8 studies | 37% ± 17% | |
| endothelial cell | 4 studies | 23% ± 5% | |
| GABAergic neuron | 3 studies | 40% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 30% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 14976.95 | 2593 / 2642 | 81% | 38.91 | 573 / 705 |
| adrenal gland | 41% | 587.00 | 105 / 258 | 92% | 130.81 | 212 / 230 |
| uterus | 21% | 375.81 | 36 / 170 | 30% | 8.25 | 136 / 459 |
| kidney | 0% | 0 | 0 / 89 | 39% | 6.15 | 352 / 901 |
| pancreas | 2% | 14.45 | 6 / 328 | 36% | 1.54 | 64 / 178 |
| esophagus | 5% | 62.16 | 78 / 1445 | 26% | 3.96 | 48 / 183 |
| eye | 0% | 0 | 0 / 0 | 28% | 2.41 | 22 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 3.48 | 11 / 45 |
| prostate | 6% | 66.17 | 14 / 245 | 16% | 0.53 | 80 / 502 |
| skin | 1% | 6.77 | 15 / 1809 | 18% | 4.50 | 87 / 472 |
| bladder | 0% | 0 | 0 / 21 | 15% | 1.72 | 76 / 504 |
| intestine | 10% | 83.62 | 97 / 966 | 5% | 0.11 | 25 / 527 |
| lung | 0% | 0 | 0 / 578 | 14% | 1.56 | 166 / 1155 |
| thymus | 0% | 0 | 0 / 653 | 9% | 5.68 | 52 / 605 |
| ovary | 7% | 61.23 | 13 / 180 | 1% | 0.04 | 4 / 430 |
| breast | 0% | 0 | 0 / 459 | 8% | 0.25 | 88 / 1118 |
| stomach | 2% | 20.64 | 7 / 359 | 5% | 0.23 | 13 / 286 |
| liver | 0% | 3.77 | 1 / 226 | 2% | 0.04 | 8 / 406 |
| muscle | 2% | 17.56 | 15 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 1.78 | 2 / 861 | 0% | 0 | 0 / 0 |
| adipose | 0% | 1.91 | 2 / 1204 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0033693 | Biological process | neurofilament bundle assembly |
| GO_0005883 | Cellular component | neurofilament |
| GO_0045111 | Cellular component | intermediate filament cytoskeleton |
| GO_0030424 | Cellular component | axon |
| GO_0097418 | Cellular component | neurofibrillary tangle |
| GO_0099160 | Cellular component | postsynaptic intermediate filament cytoskeleton |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005882 | Cellular component | intermediate filament |
| GO_0005200 | Molecular function | structural constituent of cytoskeleton |
| GO_0005515 | Molecular function | protein binding |
| GO_0008017 | Molecular function | microtubule binding |
| Gene name | NEFM |
| Protein name | Neurofilament medium polypeptide (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein) Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein) |
| Synonyms | NFM NEF3 |
| Description | FUNCTION: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). . |
| Accessions | E7EMV2 P07197 ENST00000437366.2 ENST00000433454.3 [P07197-2] E7ESP9 ENST00000221166.10 [P07197-1] ENST00000518131.5 A5YM63 |
