NECTIN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1902414Biological processprotein localization to cell junction
GO_0060041Biological processretina development in camera-type eye
GO_0007155Biological processcell adhesion
GO_0006826Biological processiron ion transport
GO_0006955Biological processimmune response
GO_0046718Biological processsymbiont entry into host cell
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0002934Biological processdesmosome organization
GO_0051963Biological processregulation of synapse assembly
GO_0002089Biological processlens morphogenesis in camera-type eye
GO_0070166Biological processenamel mineralization
GO_0098609Biological processcell-cell adhesion
GO_0007157Biological processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0007411Biological processaxon guidance
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0048787Cellular componentpresynaptic active zone membrane
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0044291Cellular componentcell-cell contact zone
GO_0030425Cellular componentdendrite
GO_0043296Cellular componentapical junction complex
GO_0005912Cellular componentadherens junction
GO_0032584Cellular componentgrowth cone membrane
GO_0015026Molecular functioncoreceptor activity
GO_0042803Molecular functionprotein homodimerization activity
GO_0044877Molecular functionprotein-containing complex binding
GO_0030246Molecular functioncarbohydrate binding
GO_0042802Molecular functionidentical protein binding
GO_0001618Molecular functionvirus receptor activity
GO_0050839Molecular functioncell adhesion molecule binding
GO_0005515Molecular functionprotein binding
GO_0046790Molecular functionvirion binding

IV. Literature review

[source]
Gene nameNECTIN1
Protein nameNectin cell adhesion molecule 1
Nectin-1
Poliovirus receptor-related 1
Poliovirus receptor-related 1 beta isoform
Poliovirus receptor-related 1 alpha isoform
Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111)
SynonymsPRR1
PVRL1
HVEC
DescriptionFUNCTION: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between NECTIN1 and NECTIN3 and between NECTIN1 and NECTIN4. Has some neurite outgrowth-promoting activity. .; FUNCTION: (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1, herpes simplex virus 2/HHV-2, and pseudorabies virus/PRV. .

AccessionsQ8WXR2
Q8WXR3
ENST00000264025.8 [Q15223-1]
Q6SYC0
Q15223
A0A8V8TKI1
ENST00000340882.2 [Q15223-3]
Q6SYC2
Q6SYC1
ENST00000531468.2