apical junction complex

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1NECTIN1-NECTIN3PVRL1_HUMAN - PVRL3_HUMANAdhesion-AdhesionAdhesion by Nectin
2NECTIN2-NECTIN3PVRL2_HUMAN - PVRL3_HUMANAdhesion-AdhesionAdhesion by Nectin

II. Literature review

[source]
Nameapical junction complex
IDGO_0043296
collection_id

Cellular component

Exact synonym

apical cell junction complex, apical junction

Description

A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.

External URL
Genes