Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 10 studies | 40% ± 18% | |
glutamatergic neuron | 10 studies | 42% ± 22% | |
endothelial cell | 7 studies | 25% ± 11% | |
astrocyte | 7 studies | 31% ± 16% | |
GABAergic neuron | 6 studies | 32% ± 15% | |
endothelial cell of lymphatic vessel | 6 studies | 28% ± 7% | |
oligodendrocyte | 6 studies | 29% ± 12% | |
epithelial cell | 4 studies | 28% ± 2% | |
neuron | 3 studies | 25% ± 8% | |
intestinal crypt stem cell | 3 studies | 27% ± 7% | |
fibroblast | 3 studies | 18% ± 1% | |
adipocyte | 3 studies | 18% ± 2% | |
interneuron | 3 studies | 37% ± 12% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 9 studies | 35% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 99% | 567.13 | 243 / 245 | 98% | 24.95 | 491 / 502 |
ovary | 100% | 1069.59 | 180 / 180 | 93% | 18.70 | 402 / 430 |
thymus | 100% | 1652.48 | 653 / 653 | 91% | 19.78 | 552 / 605 |
intestine | 100% | 988.32 | 966 / 966 | 89% | 11.06 | 467 / 527 |
stomach | 100% | 1178.95 | 359 / 359 | 88% | 13.74 | 252 / 286 |
pancreas | 96% | 341.67 | 314 / 328 | 89% | 9.44 | 159 / 178 |
kidney | 96% | 375.83 | 85 / 89 | 89% | 10.48 | 800 / 901 |
liver | 100% | 844.84 | 226 / 226 | 79% | 7.16 | 321 / 406 |
brain | 82% | 449.65 | 2157 / 2642 | 92% | 8.86 | 649 / 705 |
adrenal gland | 98% | 455.76 | 253 / 258 | 72% | 6.74 | 165 / 230 |
lung | 99% | 615.98 | 572 / 578 | 66% | 7.44 | 762 / 1155 |
bladder | 100% | 637.81 | 21 / 21 | 63% | 6.75 | 317 / 504 |
uterus | 99% | 673.55 | 168 / 170 | 56% | 5.99 | 258 / 459 |
esophagus | 72% | 491.66 | 1044 / 1445 | 64% | 8.34 | 118 / 183 |
breast | 100% | 594.53 | 457 / 459 | 20% | 1.11 | 227 / 1118 |
skin | 61% | 2200.72 | 1106 / 1809 | 52% | 4.84 | 247 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.25 | 1 / 1 |
blood vessel | 100% | 927.00 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 736.51 | 1203 / 1204 | 0% | 0 | 0 / 0 |
heart | 84% | 308.33 | 724 / 861 | 0% | 0 | 0 / 0 |
spleen | 58% | 146.21 | 139 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 47% | 3.75 | 21 / 45 |
muscle | 36% | 80.07 | 286 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.90 | 4 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1902414 | Biological process | protein localization to cell junction |
GO_0046718 | Biological process | symbiont entry into host cell |
GO_0009566 | Biological process | fertilization |
GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
GO_0060042 | Biological process | retina morphogenesis in camera-type eye |
GO_0002089 | Biological process | lens morphogenesis in camera-type eye |
GO_0061951 | Biological process | establishment of protein localization to plasma membrane |
GO_0007157 | Biological process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
GO_0098839 | Cellular component | postsynaptic density membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
GO_0044291 | Cellular component | cell-cell contact zone |
GO_0030425 | Cellular component | dendrite |
GO_0005911 | Cellular component | cell-cell junction |
GO_0043296 | Cellular component | apical junction complex |
GO_0005912 | Cellular component | adherens junction |
GO_0030424 | Cellular component | axon |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0050839 | Molecular function | cell adhesion molecule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NECTIN3 |
Protein name | Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113) Nectin cell adhesion molecule 3 |
Synonyms | PVRL3 PRR3 |
Description | FUNCTION: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body. . |
Accessions | ENST00000493615.5 [Q9NQS3-3] H7C4L0 H7C5G5 C9JMW3 C9J795 C9IZE6 ENST00000491525.5 Q9NQS3 ENST00000319792.7 [Q9NQS3-2] ENST00000485303.6 [Q9NQS3-1] ENST00000461477.5 ENST00000486596.5 ENST00000481766.1 ENST00000485506.1 |