hippocampal mossy fiber to CA3 synapse

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1EFNB3-EPHB2EFNB3_HUMAN - EPHB2_HUMANLigand-ReceptorSignaling by Ephrin
2NECTIN1-NECTIN3PVRL1_HUMAN - PVRL3_HUMANAdhesion-AdhesionAdhesion by Nectin

II. Literature review

[source]
Namehippocampal mossy fiber to CA3 synapse
IDGO_0098686
collection_id

Cellular component

Description

One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.

External URL
Genes
CTNND1PPP3R1CACNG2GRIK2RNF19AEPHB2AKAP7EFNB3GRIK5SLC6A9SLC16A7SLC30A3ADCY8C1QL2VTI1AROGDIPTPRDSYT1GPER1YWHAZNECTIN1ADCY1LRRTM2CALB1SYT9STXBP5C1QL3P2RX3PRKAR1BSYT7CAPZBSLC39A3PDYNMAL2SHANK2GRIN2DSYT12GRIK4CALCABACE1RAPGEF4NECTIN3DTNBP1