GRIK5 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	7 studies	29% ± 18%	Explore
interneuron	5 studies	30% ± 19%	Explore
neuron	4 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	4 studies	22% ± 7%	Explore
GABAergic neuron	4 studies	31% ± 14%	Explore
endothelial cell	3 studies	32% ± 11%	Explore
granule cell	3 studies	23% ± 7%	Explore
astrocyte	3 studies	24% ± 4%	Explore

Name	Number of supported studies	Average coverage
brain	6 studies	29% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	4038.67	2594 / 2642	99%	59.65	701 / 705
thymus	100%	2511.72	651 / 653	88%	19.33	533 / 605
prostate	98%	1403.77	240 / 245	50%	3.30	253 / 502
ovary	66%	596.59	118 / 180	73%	20.81	313 / 430
kidney	98%	1095.48	87 / 89	16%	2.99	142 / 901
uterus	96%	1443.85	163 / 170	16%	3.70	72 / 459
blood vessel	98%	2003.74	1308 / 1335	0%	0	0 / 0
bladder	81%	963.57	17 / 21	5%	0.84	26 / 504
adrenal gland	13%	143.72	34 / 258	67%	43.12	155 / 230
intestine	75%	1993.35	728 / 966	4%	0.38	22 / 527
esophagus	65%	1579.40	933 / 1445	7%	0.49	12 / 183
heart	54%	552.45	466 / 861	0%	0	0 / 0
stomach	42%	876.40	151 / 359	8%	0.86	24 / 286
pancreas	20%	126.22	67 / 328	29%	4.28	51 / 178
breast	20%	119.48	94 / 459	5%	0.52	53 / 1118
adipose	22%	140.32	261 / 1204	0%	0	0 / 0
lung	1%	8.53	8 / 578	10%	1.38	110 / 1155
spleen	10%	53.15	23 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	5%	0.60	4 / 80
skin	2%	10.41	36 / 1809	2%	0.20	8 / 472
lymph node	0%	0	0 / 0	3%	0.27	1 / 29
tonsil	0%	0	0 / 0	2%	0.11	1 / 45
muscle	0%	1.86	3 / 803	0%	0	0 / 0
peripheral blood	0%	0.53	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0	0 / 406
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0035235	Biological process	ionotropic glutamate receptor signaling pathway
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0031630	Biological process	regulation of synaptic vesicle fusion to presynaptic active zone membrane
GO_0050804	Biological process	modulation of chemical synaptic transmission
GO_0099505	Biological process	regulation of presynaptic membrane potential
GO_0035249	Biological process	synaptic transmission, glutamatergic
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0098839	Cellular component	postsynaptic density membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005783	Cellular component	endoplasmic reticulum
GO_0042734	Cellular component	presynaptic membrane
GO_0032983	Cellular component	kainate selective glutamate receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0098686	Cellular component	hippocampal mossy fiber to CA3 synapse
GO_0099507	Molecular function	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
GO_0004970	Molecular function	glutamate-gated receptor activity
GO_0015277	Molecular function	kainate selective glutamate receptor activity
GO_1904315	Molecular function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Gene name	GRIK5
Protein name	Putative NMDtranscript(Del_e13-e15) Glutamate receptor ionotropic, kainate 5 (GluK5) (Excitatory amino acid receptor 2) (EAA2) (Glutamate receptor KA-2) (KA2) Glutamate ionotropic receptor kainate type subunit 5 Putative NMDtranscript(AltDon_e2)
Synonyms	GRIK2
Description	FUNCTION: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R-ACPD.
Accessions	ENST00000593562.6 [Q16478-1] M0QXF6 A0A8D9UJB7 ENST00000262895.7 [Q16478-1] ENST00000301218.8 [Q16478-2] A0A8D9UIS7 ENST00000594528.1 Q16478

GRIK5 report