Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 9 studies | 45% ± 25% | |
| GABAergic neuron | 9 studies | 47% ± 26% | |
| oligodendrocyte precursor cell | 7 studies | 25% ± 7% | |
| interneuron | 6 studies | 47% ± 23% | |
| neuron | 4 studies | 26% ± 6% | |
| granule cell | 4 studies | 25% ± 3% | |
| retina horizontal cell | 4 studies | 25% ± 5% | |
| GABAergic interneuron | 3 studies | 38% ± 3% | |
| amacrine cell | 3 studies | 28% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 8 studies | 38% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 96% | 492.05 | 2534 / 2642 | 59% | 5.67 | 419 / 705 |
| adrenal gland | 9% | 8.30 | 22 / 258 | 67% | 3.45 | 154 / 230 |
| pancreas | 0% | 0 | 0 / 328 | 4% | 0.21 | 7 / 178 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| ovary | 0% | 0 | 0 / 180 | 1% | 0.12 | 4 / 430 |
| breast | 0% | 0 | 0 / 459 | 1% | 0.05 | 7 / 1118 |
| esophagus | 0% | 0 | 0 / 1445 | 1% | 0.01 | 1 / 183 |
| lung | 0% | 0 | 0 / 578 | 0% | 0.01 | 5 / 1155 |
| intestine | 0% | 0 | 0 / 966 | 0% | 0.01 | 2 / 527 |
| stomach | 0% | 0 | 0 / 359 | 0% | 0.01 | 1 / 286 |
| adipose | 0% | 0.11 | 3 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0.01 | 1 / 504 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0.00 | 1 / 605 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.01 | 1 / 901 |
| skin | 0% | 0.03 | 1 / 1809 | 0% | 0 | 0 / 472 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0 | 0 / 502 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| uterus | 0% | 0 | 0 / 170 | 0% | 0 | 0 / 459 |
| GO_0051899 | Biological process | membrane depolarization |
| GO_0060082 | Biological process | eye blink reflex |
| GO_0006612 | Biological process | protein targeting to membrane |
| GO_1904510 | Biological process | positive regulation of protein localization to basolateral plasma membrane |
| GO_0007528 | Biological process | neuromuscular junction development |
| GO_0098970 | Biological process | postsynaptic neurotransmitter receptor diffusion trapping |
| GO_0060081 | Biological process | membrane hyperpolarization |
| GO_0099590 | Biological process | neurotransmitter receptor internalization |
| GO_2000311 | Biological process | regulation of AMPA receptor activity |
| GO_0098943 | Biological process | neurotransmitter receptor transport, postsynaptic endosome to lysosome |
| GO_0051968 | Biological process | positive regulation of synaptic transmission, glutamatergic |
| GO_0019226 | Biological process | transmission of nerve impulse |
| GO_0099645 | Biological process | neurotransmitter receptor localization to postsynaptic specialization membrane |
| GO_0051592 | Biological process | response to calcium ion |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098839 | Cellular component | postsynaptic density membrane |
| GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0036477 | Cellular component | somatodendritic compartment |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0032281 | Cellular component | AMPA glutamate receptor complex |
| GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
| GO_0005891 | Cellular component | voltage-gated calcium channel complex |
| GO_0009986 | Cellular component | cell surface |
| GO_0044300 | Cellular component | cerebellar mossy fiber |
| GO_0005245 | Molecular function | voltage-gated calcium channel activity |
| GO_0016247 | Molecular function | channel regulator activity |
| GO_0035255 | Molecular function | ionotropic glutamate receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CACNG2 |
| Protein name | Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2) |
| Synonyms | |
| Description | FUNCTION: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. . |
| Accessions | Q9Y698 ENST00000300105.7 |
