Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 33% ± 17% | |
astrocyte | 15 studies | 54% ± 23% | |
oligodendrocyte precursor cell | 14 studies | 42% ± 17% | |
glutamatergic neuron | 13 studies | 66% ± 21% | |
oligodendrocyte | 13 studies | 32% ± 12% | |
mast cell | 12 studies | 54% ± 22% | |
GABAergic neuron | 11 studies | 55% ± 24% | |
microglial cell | 11 studies | 28% ± 11% | |
fibroblast | 9 studies | 32% ± 9% | |
amacrine cell | 7 studies | 44% ± 27% | |
interneuron | 7 studies | 60% ± 24% | |
macrophage | 7 studies | 32% ± 8% | |
neuron | 6 studies | 51% ± 9% | |
epithelial cell | 6 studies | 29% ± 22% | |
retinal ganglion cell | 6 studies | 58% ± 19% | |
adipocyte | 6 studies | 25% ± 5% | |
endothelial cell of lymphatic vessel | 5 studies | 28% ± 8% | |
pericyte | 5 studies | 26% ± 10% | |
smooth muscle cell | 5 studies | 25% ± 4% | |
type I pneumocyte | 5 studies | 24% ± 5% | |
type II pneumocyte | 5 studies | 19% ± 4% | |
granule cell | 4 studies | 52% ± 10% | |
cardiac muscle cell | 4 studies | 29% ± 5% | |
dendritic cell | 4 studies | 18% ± 4% | |
ciliated cell | 4 studies | 20% ± 4% | |
retina horizontal cell | 4 studies | 38% ± 17% | |
retinal cone cell | 4 studies | 34% ± 14% | |
retinal rod cell | 4 studies | 37% ± 7% | |
T cell | 4 studies | 23% ± 5% | |
monocyte | 4 studies | 34% ± 14% | |
GABAergic interneuron | 3 studies | 61% ± 1% | |
CD4-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
mesothelial cell | 3 studies | 31% ± 11% | |
GABAergic amacrine cell | 3 studies | 68% ± 12% | |
OFF-bipolar cell | 3 studies | 41% ± 6% | |
ON-bipolar cell | 3 studies | 35% ± 8% | |
glycinergic amacrine cell | 3 studies | 56% ± 4% | |
myeloid cell | 3 studies | 27% ± 9% | |
neural progenitor cell | 3 studies | 30% ± 11% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 54% ± 30% | |
alveolar macrophage | 3 studies | 22% ± 6% | |
natural killer cell | 3 studies | 22% ± 4% | |
lymphocyte | 3 studies | 34% ± 7% | |
goblet cell | 3 studies | 52% ± 34% | |
transit amplifying cell | 3 studies | 33% ± 23% | |
mucus secreting cell | 3 studies | 23% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2151.11 | 1444 / 1445 | 100% | 13.24 | 183 / 183 |
prostate | 100% | 2696.88 | 244 / 245 | 100% | 15.09 | 502 / 502 |
pancreas | 99% | 2338.77 | 326 / 328 | 99% | 10.26 | 177 / 178 |
lung | 99% | 1609.46 | 573 / 578 | 99% | 7.86 | 1145 / 1155 |
uterus | 100% | 2288.92 | 170 / 170 | 98% | 8.37 | 451 / 459 |
intestine | 100% | 2823.89 | 966 / 966 | 98% | 10.76 | 517 / 527 |
bladder | 100% | 1997.43 | 21 / 21 | 98% | 8.71 | 494 / 504 |
adrenal gland | 100% | 3272.51 | 258 / 258 | 98% | 16.06 | 225 / 230 |
breast | 100% | 1832.63 | 459 / 459 | 98% | 9.45 | 1093 / 1118 |
thymus | 100% | 1939.83 | 652 / 653 | 98% | 7.22 | 591 / 605 |
stomach | 98% | 1315.01 | 351 / 359 | 98% | 10.72 | 281 / 286 |
skin | 100% | 5003.78 | 1808 / 1809 | 93% | 10.29 | 440 / 472 |
brain | 98% | 3006.86 | 2587 / 2642 | 91% | 6.70 | 644 / 705 |
ovary | 100% | 1355.84 | 180 / 180 | 82% | 4.23 | 353 / 430 |
kidney | 82% | 700.01 | 73 / 89 | 84% | 4.19 | 759 / 901 |
spleen | 100% | 2074.93 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.43 | 1 / 1 |
blood vessel | 100% | 2566.78 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 1778.68 | 1202 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 1558.91 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 92% | 1002.24 | 790 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 5.91 | 41 / 45 |
peripheral blood | 86% | 1975.51 | 798 / 929 | 0% | 0 | 0 / 0 |
liver | 31% | 190.17 | 71 / 226 | 49% | 2.26 | 198 / 406 |
lymph node | 0% | 0 | 0 / 0 | 76% | 3.86 | 22 / 29 |
eye | 0% | 0 | 0 / 0 | 63% | 3.98 | 50 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0017157 | Biological process | regulation of exocytosis |
GO_0006887 | Biological process | exocytosis |
GO_0010807 | Biological process | regulation of synaptic vesicle priming |
GO_0006893 | Biological process | Golgi to plasma membrane transport |
GO_0015031 | Biological process | protein transport |
GO_0045921 | Biological process | positive regulation of exocytosis |
GO_2000300 | Biological process | regulation of synaptic vesicle exocytosis |
GO_0098674 | Cellular component | extrinsic component of neuronal dense core vesicle membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
GO_0005829 | Cellular component | cytosol |
GO_0008021 | Cellular component | synaptic vesicle |
GO_0005737 | Cellular component | cytoplasm |
GO_0005892 | Cellular component | acetylcholine-gated channel complex |
GO_0031201 | Cellular component | SNARE complex |
GO_0045159 | Molecular function | myosin II binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0017075 | Molecular function | syntaxin-1 binding |
GO_0019905 | Molecular function | syntaxin binding |
Gene name | STXBP5 |
Protein name | Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1) Syntaxin binding protein 5 STXBP5 protein Syntaxin binding protein 5 (Tomosyn) |
Synonyms | LLGL3 hCG_16767 |
Description | FUNCTION: Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity). . |
Accessions | F6VFW0 H0Y332 Q3B794 ENST00000367475.7 ENST00000706849.1 [Q5T5C0-2] ENST00000367481.7 [Q5T5C0-2] Q5T5C0 A0A9L9PY07 ENST00000706854.1 ENST00000321680.11 [Q5T5C0-1] ENST00000706851.1 ENST00000706850.1 [Q5T5C0-2] A0A9L9PXY2 ENST00000367480.7 [Q5T5C0-3] ENST00000546097.5 Q14DD4 |