PTPRD report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006470Biological processprotein dephosphorylation
GO_0050804Biological processmodulation of chemical synaptic transmission
GO_0046426Biological processnegative regulation of receptor signaling pathway via JAK-STAT
GO_0061003Biological processpositive regulation of dendritic spine morphogenesis
GO_0099560Biological processsynaptic membrane adhesion
GO_0006796Biological processphosphate-containing compound metabolic process
GO_0050776Biological processregulation of immune response
GO_0030182Biological processneuron differentiation
GO_0007185Biological processcell surface receptor protein tyrosine phosphatase signaling pathway
GO_0099545Biological processtrans-synaptic signaling by trans-synaptic complex
GO_0099054Biological processpresynapse assembly
GO_0051965Biological processpositive regulation of synapse assembly
GO_0007157Biological processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0097105Biological processpresynaptic membrane assembly
GO_0099151Biological processregulation of postsynaptic density assembly
GO_0098978Cellular componentglutamatergic synapse
GO_0098685Cellular componentSchaffer collateral - CA1 synapse
GO_0005886Cellular componentplasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0042734Cellular componentpresynaptic membrane
GO_0005001Molecular functiontransmembrane receptor protein tyrosine phosphatase activity
GO_0005102Molecular functionsignaling receptor binding
GO_0050839Molecular functioncell adhesion molecule binding
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene namePTPRD
Protein nameRceptor-type tyrosine-protein phosphatase delta
protein-tyrosine-phosphatase (EC 3.1.3.48)
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)
Protein tyrosine phosphatase receptor type D
Synonyms
DescriptionFUNCTION: Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2. .

AccessionsENST00000637354.1
ENST00000355233.9 [P23468-6]
ENST00000481079.1
P23468
ENST00000356435.9 [P23468-1]
ENST00000463477.5
Q2HXI4
A0A1Y0ZSN9
ENST00000537002.5
ENST00000397606.7 [P23468-4]
ENST00000381196.9 [P23468-1]
ENST00000540109.5 [P23468-1]
ENST00000397617.8
ENST00000397611.7 [P23468-7]
C9J8S8
F5GWR7
A0A1B0GU15
C9J6E4
ENST00000486161.5 [P23468-5]
Q3KPI9
A0A1Y0ZJV0