presynapse assembly

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
FZD1
retina horizontal celladipocyte
3 studies
Group 2
DVL1SDCBP
epithelial cellneuron
5 studies
Group 3
NLGN2PTPRDCNTN5NLGN1NLGN4X
dopaminergic neuronGABAergic neuronglutamatergic neuroninterneuron
7 studies
Group 4
NLGN4YNLGN3
oligodendrocyte precursor cell
8 studies
Group 5
WNT5A
fibroblastgoblet cellmicroglial cell
4 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1NLGN3-PTPRDNLGN3_HUMAN - PTPRD_HUMANLigand-ReceptorSignaling by Neuroligin
2WNT3A-FZD1+LRP5WNT3A_HUMAN - Ligand-ReceptorSignaling by WNT
3WNT3A-FZD1+LRP6WNT3A_HUMAN - Ligand-ReceptorSignaling by WNT
4WNT7A-FZD1+LRP5WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT
5WNT7A-FZD1+LRP6WNT7A_HUMAN - Ligand-ReceptorSignaling by WNT

III. Literature review

[source]
Namepresynapse assembly
IDGO_0099054
collection_id

Biological process

Exact synonym

presynapse biogenesis, presynaptic terminal assembly

Description

The aggregation, arrangement and bonding together of a set of components to form a presynapse.

External URL
Genes
NLGN4XNLGN1DVL1WNT5ANLGN2WNT7ACNTN5PTPRDSDCBPWNT3ANLGN4YFZD1NLGN3