Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 9 studies | 41% ± 18% | |
| oligodendrocyte | 5 studies | 20% ± 4% | |
| GABAergic neuron | 3 studies | 26% ± 2% | |
| astrocyte | 3 studies | 19% ± 2% | |
| glutamatergic neuron | 3 studies | 29% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 3715.85 | 2641 / 2642 | 100% | 167.28 | 703 / 705 |
| prostate | 87% | 737.53 | 213 / 245 | 87% | 6.47 | 439 / 502 |
| adrenal gland | 97% | 2033.47 | 249 / 258 | 49% | 9.61 | 112 / 230 |
| ovary | 81% | 682.05 | 146 / 180 | 49% | 3.14 | 210 / 430 |
| uterus | 49% | 322.19 | 83 / 170 | 24% | 1.75 | 111 / 459 |
| intestine | 52% | 322.38 | 506 / 966 | 13% | 0.54 | 68 / 527 |
| pancreas | 0% | 0 | 0 / 328 | 62% | 2.71 | 111 / 178 |
| skin | 2% | 8.93 | 40 / 1809 | 57% | 8.12 | 271 / 472 |
| esophagus | 37% | 210.21 | 528 / 1445 | 23% | 0.78 | 42 / 183 |
| peripheral blood | 49% | 302.72 | 451 / 929 | 0% | 0 | 0 / 0 |
| stomach | 15% | 78.63 | 53 / 359 | 26% | 1.11 | 75 / 286 |
| blood vessel | 31% | 157.57 | 416 / 1335 | 0% | 0 | 0 / 0 |
| lung | 9% | 37.62 | 53 / 578 | 21% | 0.72 | 239 / 1155 |
| bladder | 14% | 61.33 | 3 / 21 | 14% | 0.65 | 71 / 504 |
| breast | 8% | 33.96 | 37 / 459 | 20% | 0.64 | 224 / 1118 |
| eye | 0% | 0 | 0 / 0 | 25% | 0.98 | 20 / 80 |
| spleen | 25% | 107.07 | 60 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 0.65 | 6 / 29 |
| kidney | 4% | 25.44 | 4 / 89 | 9% | 0.33 | 85 / 901 |
| heart | 13% | 61.89 | 109 / 861 | 0% | 0 | 0 / 0 |
| thymus | 5% | 19.37 | 30 / 653 | 7% | 0.21 | 41 / 605 |
| adipose | 9% | 39.44 | 109 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.24 | 4 / 45 |
| liver | 0% | 0 | 0 / 226 | 4% | 0.12 | 15 / 406 |
| muscle | 0% | 0.58 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0002087 | Biological process | regulation of respiratory gaseous exchange by nervous system process |
| GO_0097104 | Biological process | postsynaptic membrane assembly |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0006898 | Biological process | receptor-mediated endocytosis |
| GO_0007612 | Biological process | learning |
| GO_0048488 | Biological process | synaptic vesicle endocytosis |
| GO_2000463 | Biological process | positive regulation of excitatory postsynaptic potential |
| GO_0071625 | Biological process | vocalization behavior |
| GO_0060024 | Biological process | rhythmic synaptic transmission |
| GO_1900451 | Biological process | positive regulation of glutamate receptor signaling pathway |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0099054 | Biological process | presynapse assembly |
| GO_0030534 | Biological process | adult behavior |
| GO_0048675 | Biological process | axon extension |
| GO_0051968 | Biological process | positive regulation of synaptic transmission, glutamatergic |
| GO_0007416 | Biological process | synapse assembly |
| GO_0035176 | Biological process | social behavior |
| GO_0050808 | Biological process | synapse organization |
| GO_0007158 | Biological process | neuron cell-cell adhesion |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_0097105 | Biological process | presynaptic membrane assembly |
| GO_0060080 | Biological process | inhibitory postsynaptic potential |
| GO_0098793 | Cellular component | presynapse |
| GO_0098985 | Cellular component | asymmetric, glutamatergic, excitatory synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030139 | Cellular component | endocytic vesicle |
| GO_0016020 | Cellular component | membrane |
| GO_0009986 | Cellular component | cell surface |
| GO_0045202 | Cellular component | synapse |
| GO_0099634 | Cellular component | postsynaptic specialization membrane |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0060076 | Cellular component | excitatory synapse |
| GO_0098983 | Cellular component | symmetric, GABA-ergic, inhibitory synapse |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0042043 | Molecular function | neurexin family protein binding |
| GO_0097110 | Molecular function | scaffold protein binding |
| GO_0050839 | Molecular function | cell adhesion molecule binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NLGN3 |
| Protein name | Neuroligin 3 isoform E Neuroligin 3 isoform C Neuroligin 3 Neuroligin-3 (Gliotactin homolog) Neuroligin 3 isoform A Neuroligin 3 isoform 2 Neuroligin 3 isoform D Neuroligin 3 isoform 1 (Neuroligin 3 isoform B) NLGN3 protein |
| Synonyms | KIAA1480 hCG_1724001 NL3 |
| Description | FUNCTION: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity). . |
| Accessions | ENST00000374051.7 [Q9NZ94-2] A0A8I5QJU7 A0A8I5QL38 ENST00000687568.1 ENST00000690293.1 ENST00000358741.4 [Q9NZ94-1] ENST00000690133.1 Q4G160 ENST00000692338.1 X5D7L6 ENST00000395855.7 A0A8I5KSX7 ENST00000687220.1 A0A8I5KTH4 A0A0S2Z5K2 ENST00000685718.1 ENST00000689857.1 ENST00000692905.1 A0A8I5KSW0 A0A8I5QJH8 A0A8I5KVP5 ENST00000688566.1 X5DNV3 X5D2P6 E7EVK0 A0A8I5KSB7 ENST00000687470.1 X5D307 A0A8I5KQ26 X5D9J9 X5DRC3 ENST00000536169.6 [Q9NZ94-3] Q9NZ94 ENST00000689968.1 |
