NLGN4X | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
astrocyte	15 studies	41% ± 13%	Explore
oligodendrocyte precursor cell	14 studies	68% ± 19%	Explore
glutamatergic neuron	12 studies	51% ± 21%	Explore
GABAergic neuron	10 studies	50% ± 26%	Explore
neuron	7 studies	31% ± 16%	Explore
interneuron	6 studies	57% ± 20%	Explore
oligodendrocyte	6 studies	28% ± 14%	Explore
amacrine cell	5 studies	26% ± 11%	Explore
endothelial cell	4 studies	37% ± 17%	Explore
glial cell	4 studies	37% ± 12%	Explore
fibroblast	4 studies	31% ± 7%	Explore
Mueller cell	4 studies	33% ± 18%	Explore
GABAergic interneuron	3 studies	53% ± 2%	Explore
granule cell	3 studies	40% ± 3%	Explore
GABAergic amacrine cell	3 studies	39% ± 12%	Explore
glycinergic amacrine cell	3 studies	28% ± 11%	Explore
retinal cone cell	3 studies	41% ± 22%	Explore
Schwann cell	3 studies	42% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	15 studies	41% ± 20%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1597.47	2635 / 2642	99%	29.90	701 / 705
ovary	98%	3223.66	177 / 180	46%	3.10	198 / 430
breast	91%	423.01	417 / 459	40%	2.83	445 / 1118
uterus	85%	473.01	145 / 170	33%	3.43	151 / 459
intestine	97%	785.30	937 / 966	7%	0.42	37 / 527
bladder	81%	427.24	17 / 21	23%	1.73	115 / 504
prostate	82%	308.53	200 / 245	20%	0.87	99 / 502
ureter	0%	0	0 / 0	100%	5.92	1 / 1
esophagus	65%	302.61	941 / 1445	30%	2.73	54 / 183
adipose	83%	418.97	994 / 1204	0%	0	0 / 0
thymus	68%	189.47	441 / 653	14%	2.10	86 / 605
heart	81%	567.24	701 / 861	0%	0	0 / 0
spleen	80%	275.30	194 / 241	0%	0	0 / 0
stomach	59%	208.09	212 / 359	12%	0.85	33 / 286
lung	51%	175.32	292 / 578	19%	1.60	222 / 1155
blood vessel	54%	222.58	725 / 1335	0%	0	0 / 0
skin	23%	60.35	417 / 1809	26%	4.31	123 / 472
adrenal gland	9%	23.86	22 / 258	39%	2.86	89 / 230
kidney	16%	44.15	14 / 89	29%	1.44	261 / 901
liver	20%	45.07	46 / 226	18%	1.43	72 / 406
pancreas	1%	1.11	2 / 328	29%	1.69	52 / 178
tonsil	0%	0	0 / 0	9%	1.04	4 / 45
peripheral blood	4%	22.58	37 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.11	1 / 29
eye	0%	0	0 / 0	3%	0.12	2 / 80
muscle	1%	3.73	11 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0035265	Biological process	organ growth
GO_0097104	Biological process	postsynaptic membrane assembly
GO_0050804	Biological process	modulation of chemical synaptic transmission
GO_0007612	Biological process	learning
GO_0048488	Biological process	synaptic vesicle endocytosis
GO_0045216	Biological process	cell-cell junction organization
GO_0071625	Biological process	vocalization behavior
GO_0030182	Biological process	neuron differentiation
GO_0007268	Biological process	chemical synaptic transmission
GO_0051963	Biological process	regulation of synapse assembly
GO_0003360	Biological process	brainstem development
GO_0099054	Biological process	presynapse assembly
GO_0090394	Biological process	negative regulation of excitatory postsynaptic potential
GO_0030534	Biological process	adult behavior
GO_0021549	Biological process	cerebellum development
GO_0035176	Biological process	social behavior
GO_0050808	Biological process	synapse organization
GO_0007158	Biological process	neuron cell-cell adhesion
GO_0097105	Biological process	presynaptic membrane assembly
GO_0098978	Cellular component	glutamatergic synapse
GO_0098839	Cellular component	postsynaptic density membrane
GO_0098793	Cellular component	presynapse
GO_0098985	Cellular component	asymmetric, glutamatergic, excitatory synapse
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0030425	Cellular component	dendrite
GO_0098982	Cellular component	GABA-ergic synapse
GO_0009986	Cellular component	cell surface
GO_0045202	Cellular component	synapse
GO_0099634	Cellular component	postsynaptic specialization membrane
GO_0060076	Cellular component	excitatory synapse
GO_0098983	Cellular component	symmetric, GABA-ergic, inhibitory synapse
GO_0042803	Molecular function	protein homodimerization activity
GO_0038023	Molecular function	signaling receptor activity
GO_0031404	Molecular function	chloride ion binding
GO_0042043	Molecular function	neurexin family protein binding
GO_0097110	Molecular function	scaffold protein binding
GO_0050839	Molecular function	cell adhesion molecule binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	NLGN4X
Protein name	Neuroligin-4, X-linked (Neuroligin X) (HNLX) Neuroligin 4 X-linked
Synonyms	UNQ365/PRO701 NLGN4 KIAA1260
Description	FUNCTION: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. .
Accessions	ENST00000538097.6 [Q8N0W4-2] ENST00000381092.1 [Q8N0W4-1] ENST00000483337.1 ENST00000381093.6 [Q8N0W4-1] A0A2R8YCI5 Q8N0W4 ENST00000275857.10 [Q8N0W4-1] A0A2R8Y6F7 ENST00000381095.8 [Q8N0W4-1] ENST00000469740.1

NLGN4X report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review