Name | Number of supported studies | Average coverage | |
---|---|---|---|
GABAergic neuron | 3 studies | 38% ± 7% | |
glutamatergic neuron | 3 studies | 44% ± 8% | |
oligodendrocyte precursor cell | 3 studies | 35% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 28% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1632.79 | 2634 / 2642 | 99% | 23.87 | 700 / 705 |
adrenal gland | 7% | 13.44 | 19 / 258 | 65% | 8.17 | 149 / 230 |
adipose | 46% | 111.87 | 557 / 1204 | 0% | 0 | 0 / 0 |
breast | 36% | 71.87 | 165 / 459 | 5% | 0.28 | 53 / 1118 |
skin | 2% | 3.59 | 41 / 1809 | 29% | 0.91 | 139 / 472 |
spleen | 18% | 32.12 | 44 / 241 | 0% | 0 | 0 / 0 |
esophagus | 1% | 1.13 | 11 / 1445 | 17% | 0.32 | 31 / 183 |
pancreas | 9% | 12.62 | 29 / 328 | 6% | 0.30 | 11 / 178 |
eye | 0% | 0 | 0 / 0 | 15% | 0.33 | 12 / 80 |
intestine | 11% | 16.82 | 108 / 966 | 3% | 0.16 | 15 / 527 |
lung | 5% | 8.65 | 30 / 578 | 9% | 0.55 | 99 / 1155 |
uterus | 5% | 7.31 | 9 / 170 | 5% | 0.15 | 22 / 459 |
thymus | 8% | 12.13 | 55 / 653 | 0% | 0.01 | 3 / 605 |
ovary | 6% | 8.28 | 11 / 180 | 1% | 0.04 | 6 / 430 |
stomach | 2% | 2.80 | 7 / 359 | 5% | 0.39 | 15 / 286 |
kidney | 2% | 2.91 | 2 / 89 | 4% | 0.18 | 37 / 901 |
bladder | 0% | 0 | 0 / 21 | 4% | 0.41 | 19 / 504 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
muscle | 1% | 1.92 | 12 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 2.20 | 16 / 1335 | 0% | 0 | 0 / 0 |
prostate | 0% | 0 | 0 / 245 | 1% | 0.05 | 5 / 502 |
liver | 0% | 0 | 0 / 226 | 0% | 0.00 | 1 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002091 | Biological process | negative regulation of receptor internalization |
GO_0050808 | Biological process | synapse organization |
GO_0051965 | Biological process | positive regulation of synapse assembly |
GO_0060291 | Biological process | long-term synaptic potentiation |
GO_0099151 | Biological process | regulation of postsynaptic density assembly |
GO_0099634 | Cellular component | postsynaptic specialization membrane |
GO_0005615 | Cellular component | extracellular space |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0060076 | Cellular component | excitatory synapse |
GO_0098839 | Cellular component | postsynaptic density membrane |
GO_0098982 | Cellular component | GABA-ergic synapse |
GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
GO_0042043 | Molecular function | neurexin family protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | LRRTM2 |
Protein name | Leucine rich repeat transmembrane neuronal 2 Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein) |
Synonyms | KIAA0416 LRRN2 |
Description | FUNCTION: Involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity). . |
Accessions | E5RHE5 E5RIQ2 ENST00000518785.1 ENST00000521094.2 O43300 ENST00000274711.7 |