Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 10 studies | 42% ± 26% | |
glutamatergic neuron | 10 studies | 62% ± 22% | |
GABAergic neuron | 9 studies | 57% ± 24% | |
endothelial cell | 6 studies | 37% ± 18% | |
interneuron | 6 studies | 61% ± 23% | |
retina horizontal cell | 6 studies | 62% ± 24% | |
club cell | 6 studies | 41% ± 22% | |
type I pneumocyte | 6 studies | 59% ± 20% | |
epithelial cell | 5 studies | 40% ± 25% | |
type II pneumocyte | 5 studies | 47% ± 11% | |
cholangiocyte | 4 studies | 68% ± 17% | |
hepatocyte | 4 studies | 64% ± 28% | |
neuron | 4 studies | 34% ± 15% | |
oligodendrocyte precursor cell | 4 studies | 19% ± 3% | |
retinal pigment epithelial cell | 4 studies | 41% ± 27% | |
amacrine cell | 4 studies | 47% ± 9% | |
GABAergic interneuron | 3 studies | 55% ± 8% | |
granule cell | 3 studies | 34% ± 18% | |
GABAergic amacrine cell | 3 studies | 46% ± 5% | |
glycinergic amacrine cell | 3 studies | 46% ± 4% | |
astrocyte | 3 studies | 46% ± 27% | |
basal cell | 3 studies | 45% ± 15% | |
respiratory goblet cell | 3 studies | 48% ± 28% | |
mucus secreting cell | 3 studies | 49% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 93% | 1199.88 | 229 / 245 | 95% | 7.96 | 475 / 502 |
kidney | 100% | 1319.45 | 89 / 89 | 88% | 5.95 | 793 / 901 |
liver | 100% | 1170.86 | 226 / 226 | 75% | 4.72 | 303 / 406 |
stomach | 88% | 856.07 | 316 / 359 | 81% | 4.45 | 231 / 286 |
breast | 73% | 1165.83 | 336 / 459 | 94% | 11.13 | 1056 / 1118 |
pancreas | 100% | 1218.05 | 328 / 328 | 67% | 2.80 | 119 / 178 |
esophagus | 80% | 917.85 | 1158 / 1445 | 84% | 9.43 | 154 / 183 |
intestine | 89% | 1117.06 | 860 / 966 | 73% | 3.50 | 386 / 527 |
lung | 92% | 1098.87 | 534 / 578 | 68% | 4.29 | 783 / 1155 |
brain | 93% | 2692.85 | 2453 / 2642 | 66% | 5.04 | 464 / 705 |
thymus | 100% | 2781.03 | 650 / 653 | 47% | 2.40 | 286 / 605 |
bladder | 67% | 499.62 | 14 / 21 | 56% | 2.40 | 281 / 504 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.07 | 1 / 1 |
skin | 63% | 444.56 | 1135 / 1809 | 4% | 0.24 | 19 / 472 |
ovary | 2% | 5.20 | 3 / 180 | 55% | 2.49 | 235 / 430 |
adrenal gland | 26% | 104.94 | 68 / 258 | 27% | 0.99 | 61 / 230 |
spleen | 44% | 191.70 | 105 / 241 | 0% | 0 | 0 / 0 |
uterus | 10% | 108.10 | 17 / 170 | 31% | 1.37 | 142 / 459 |
tonsil | 0% | 0 | 0 / 0 | 18% | 0.97 | 8 / 45 |
adipose | 12% | 52.98 | 150 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.76 | 1 / 29 |
peripheral blood | 3% | 25.28 | 32 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.04 | 1 / 80 |
blood vessel | 0% | 0.64 | 2 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007584 | Biological process | response to nutrient |
GO_0007612 | Biological process | learning |
GO_0008344 | Biological process | adult locomotory behavior |
GO_0099562 | Biological process | maintenance of postsynaptic density structure |
GO_0008306 | Biological process | associative learning |
GO_0060292 | Biological process | long-term synaptic depression |
GO_0060291 | Biological process | long-term synaptic potentiation |
GO_0071625 | Biological process | vocalization behavior |
GO_0030534 | Biological process | adult behavior |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0007416 | Biological process | synapse assembly |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0035176 | Biological process | social behavior |
GO_0099175 | Biological process | regulation of postsynapse organization |
GO_0035331 | Biological process | negative regulation of hippo signaling |
GO_0031526 | Cellular component | brush border membrane |
GO_0005575 | Cellular component | cellular_component |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0043197 | Cellular component | dendritic spine |
GO_0001750 | Cellular component | photoreceptor outer segment |
GO_0005883 | Cellular component | neurofilament |
GO_0001917 | Cellular component | photoreceptor inner segment |
GO_0043025 | Cellular component | neuronal cell body |
GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
GO_0043005 | Cellular component | neuron projection |
GO_0060170 | Cellular component | ciliary membrane |
GO_0048786 | Cellular component | presynaptic active zone |
GO_0005829 | Cellular component | cytosol |
GO_0014069 | Cellular component | postsynaptic density |
GO_0030426 | Cellular component | growth cone |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0098919 | Molecular function | structural constituent of postsynaptic density |
GO_0030160 | Molecular function | synaptic receptor adaptor activity |
GO_0035255 | Molecular function | ionotropic glutamate receptor binding |
GO_0005515 | Molecular function | protein binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | SHANK2 |
Protein name | SHANK2 SHANK2 protein SH3 and multiple ankyrin repeat domains 2 Cortactin-binding protein 1 (SH3 and multiple ankyrin repeat domains 2) Alternative protein SHANK2 SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1) |
Synonyms | CORTBP1 KIAA1022 PROSAP1 |
Description | FUNCTION: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction. |
Accessions | H0Y7S5 I7D9N1 ENST00000426687.2 Q24JS4 ENST00000645599.1 ENST00000338508.9 ENST00000412252.6 E7EUA2 H7BZV1 A0A2R8Y2H5 ENST00000654939.1 A0A590UJF3 A6NHU9 B7ZKU9 ENST00000656230.1 [Q9UPX8-1] Q9UPX8 ENST00000601538.6 [Q9UPX8-3] A0A590UJ45 ENST00000409161.5 ENST00000659264.1 I7C337 L8E8F5 |