Insufficient scRNA-seq data for expression of P2RX3 at single-cell level.
Insufficient scRNA-seq data for expression of P2RX3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 94% | 34.38 | 212 / 226 | 20% | 0.44 | 80 / 406 |
adrenal gland | 94% | 27.10 | 243 / 258 | 12% | 0.36 | 28 / 230 |
stomach | 82% | 20.39 | 296 / 359 | 17% | 0.56 | 48 / 286 |
heart | 79% | 91.80 | 679 / 861 | 0% | 0 | 0 / 0 |
intestine | 56% | 5.85 | 538 / 966 | 7% | 0.22 | 35 / 527 |
pancreas | 48% | 3.86 | 156 / 328 | 13% | 0.36 | 23 / 178 |
bladder | 38% | 4.95 | 8 / 21 | 2% | 0.10 | 12 / 504 |
esophagus | 29% | 3.89 | 413 / 1445 | 11% | 0.25 | 21 / 183 |
uterus | 32% | 2.09 | 54 / 170 | 4% | 0.30 | 19 / 459 |
thymus | 33% | 2.16 | 214 / 653 | 2% | 0.03 | 13 / 605 |
adipose | 33% | 3.28 | 399 / 1204 | 0% | 0 | 0 / 0 |
prostate | 33% | 2.86 | 80 / 245 | 0% | 0 | 0 / 502 |
brain | 29% | 1.82 | 766 / 2642 | 3% | 0.07 | 23 / 705 |
ovary | 21% | 1.13 | 37 / 180 | 10% | 0.88 | 43 / 430 |
muscle | 29% | 2.42 | 229 / 803 | 0% | 0 | 0 / 0 |
lung | 22% | 1.29 | 128 / 578 | 3% | 0.14 | 37 / 1155 |
breast | 22% | 1.47 | 101 / 459 | 0% | 0.01 | 1 / 1118 |
kidney | 10% | 0.76 | 9 / 89 | 4% | 0.07 | 39 / 901 |
spleen | 10% | 0.54 | 23 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 7% | 0.72 | 97 / 1335 | 0% | 0 | 0 / 0 |
skin | 6% | 0.34 | 111 / 1809 | 1% | 0.01 | 3 / 472 |
peripheral blood | 3% | 0.19 | 31 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009408 | Biological process | response to heat |
GO_0050850 | Biological process | positive regulation of calcium-mediated signaling |
GO_0010524 | Biological process | positive regulation of calcium ion transport into cytosol |
GO_0060079 | Biological process | excitatory postsynaptic potential |
GO_0007165 | Biological process | signal transduction |
GO_0035590 | Biological process | purinergic nucleotide receptor signaling pathway |
GO_0070207 | Biological process | protein homotrimerization |
GO_0098662 | Biological process | inorganic cation transmembrane transport |
GO_0007274 | Biological process | neuromuscular synaptic transmission |
GO_0051649 | Biological process | establishment of localization in cell |
GO_0071318 | Biological process | cellular response to ATP |
GO_0050909 | Biological process | sensory perception of taste |
GO_0048167 | Biological process | regulation of synaptic plasticity |
GO_0014832 | Biological process | urinary bladder smooth muscle contraction |
GO_0009409 | Biological process | response to cold |
GO_0001666 | Biological process | response to hypoxia |
GO_0009743 | Biological process | response to carbohydrate |
GO_0009612 | Biological process | response to mechanical stimulus |
GO_0048266 | Biological process | behavioral response to pain |
GO_0030432 | Biological process | peristalsis |
GO_0070588 | Biological process | calcium ion transmembrane transport |
GO_0043235 | Cellular component | receptor complex |
GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0098794 | Cellular component | postsynapse |
GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
GO_0030424 | Cellular component | axon |
GO_0001614 | Molecular function | purinergic nucleotide receptor activity |
GO_0005524 | Molecular function | ATP binding |
GO_0004931 | Molecular function | extracellularly ATP-gated monoatomic cation channel activity |
Gene name | P2RX3 |
Protein name | P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor) Purinergic receptor P2X 3 |
Synonyms | |
Description | FUNCTION: Receptor for ATP that acts as a ligand-gated cation channel . Plays a role in sensory perception. Required for normal perception of pain. Required for normal taste perception (By similarity). . |
Accessions | P56373 ENST00000263314.3 ENST00000534820.1 H0YDR6 |