P2RX3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of P2RX3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of P2RX3 at tissue level.

III. Associated gene sets

GO_0009408Biological processresponse to heat
GO_0050850Biological processpositive regulation of calcium-mediated signaling
GO_0010524Biological processpositive regulation of calcium ion transport into cytosol
GO_0060079Biological processexcitatory postsynaptic potential
GO_0007165Biological processsignal transduction
GO_0035590Biological processpurinergic nucleotide receptor signaling pathway
GO_0070207Biological processprotein homotrimerization
GO_0098662Biological processinorganic cation transmembrane transport
GO_0007274Biological processneuromuscular synaptic transmission
GO_0051649Biological processestablishment of localization in cell
GO_0071318Biological processcellular response to ATP
GO_0050909Biological processsensory perception of taste
GO_0048167Biological processregulation of synaptic plasticity
GO_0014832Biological processurinary bladder smooth muscle contraction
GO_0009409Biological processresponse to cold
GO_0001666Biological processresponse to hypoxia
GO_0009743Biological processresponse to carbohydrate
GO_0009612Biological processresponse to mechanical stimulus
GO_0048266Biological processbehavioral response to pain
GO_0030432Biological processperistalsis
GO_0070588Biological processcalcium ion transmembrane transport
GO_0043235Cellular componentreceptor complex
GO_0098685Cellular componentSchaffer collateral - CA1 synapse
GO_0005886Cellular componentplasma membrane
GO_0098794Cellular componentpostsynapse
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0030424Cellular componentaxon
GO_0001614Molecular functionpurinergic nucleotide receptor activity
GO_0005524Molecular functionATP binding
GO_0004931Molecular functionextracellularly ATP-gated monoatomic cation channel activity

IV. Literature review

[source]
Gene nameP2RX3
Protein nameP2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor)
Purinergic receptor P2X 3
Synonyms
DescriptionFUNCTION: Receptor for ATP that acts as a ligand-gated cation channel . Plays a role in sensory perception. Required for normal perception of pain. Required for normal taste perception (By similarity). .

AccessionsP56373
ENST00000263314.3
ENST00000534820.1
H0YDR6