Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 14 studies | 34% ± 15% | |
| oligodendrocyte precursor cell | 13 studies | 48% ± 20% | |
| glutamatergic neuron | 9 studies | 35% ± 20% | |
| GABAergic neuron | 8 studies | 38% ± 14% | |
| oligodendrocyte | 8 studies | 31% ± 13% | |
| retinal cone cell | 4 studies | 40% ± 15% | |
| interneuron | 4 studies | 44% ± 25% | |
| GABAergic interneuron | 3 studies | 39% ± 33% | |
| neuron | 3 studies | 30% ± 9% | |
| ependymal cell | 3 studies | 41% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 11 studies | 33% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 983.73 | 2638 / 2642 | 99% | 22.25 | 701 / 705 |
| adrenal gland | 100% | 431.40 | 257 / 258 | 77% | 3.70 | 177 / 230 |
| ovary | 94% | 475.27 | 170 / 180 | 31% | 0.87 | 132 / 430 |
| thymus | 87% | 387.50 | 566 / 653 | 35% | 1.72 | 209 / 605 |
| lung | 96% | 410.43 | 555 / 578 | 6% | 0.12 | 65 / 1155 |
| breast | 28% | 135.80 | 127 / 459 | 40% | 1.26 | 444 / 1118 |
| spleen | 59% | 97.46 | 142 / 241 | 0% | 0 | 0 / 0 |
| prostate | 49% | 76.67 | 119 / 245 | 6% | 0.18 | 29 / 502 |
| kidney | 11% | 17.44 | 10 / 89 | 14% | 0.46 | 124 / 901 |
| peripheral blood | 23% | 47.16 | 215 / 929 | 0% | 0 | 0 / 0 |
| bladder | 10% | 13.52 | 2 / 21 | 9% | 0.20 | 43 / 504 |
| skin | 12% | 18.31 | 217 / 1809 | 5% | 0.19 | 25 / 472 |
| uterus | 5% | 7.32 | 8 / 170 | 11% | 0.33 | 52 / 459 |
| esophagus | 12% | 16.42 | 169 / 1445 | 4% | 0.09 | 7 / 183 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.30 | 4 / 29 |
| heart | 11% | 14.39 | 98 / 861 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 11% | 0.22 | 46 / 406 |
| eye | 0% | 0 | 0 / 0 | 6% | 0.10 | 5 / 80 |
| intestine | 3% | 3.72 | 30 / 966 | 2% | 0.02 | 8 / 527 |
| stomach | 0% | 0 | 0 / 359 | 4% | 0.07 | 11 / 286 |
| pancreas | 0% | 0 | 0 / 328 | 2% | 0.03 | 4 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.18 | 1 / 45 |
| adipose | 1% | 1.39 | 12 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.83 | 3 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.34 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060078 | Biological process | regulation of postsynaptic membrane potential |
| GO_0035235 | Biological process | ionotropic glutamate receptor signaling pathway |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0007215 | Biological process | glutamate receptor signaling pathway |
| GO_0099505 | Biological process | regulation of presynaptic membrane potential |
| GO_0035249 | Biological process | synaptic transmission, glutamatergic |
| GO_0098839 | Cellular component | postsynaptic density membrane |
| GO_0042734 | Cellular component | presynaptic membrane |
| GO_0032983 | Cellular component | kainate selective glutamate receptor complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0098686 | Cellular component | hippocampal mossy fiber to CA3 synapse |
| GO_0099507 | Molecular function | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
| GO_0015277 | Molecular function | kainate selective glutamate receptor activity |
| GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
| Gene name | GRIK4 |
| Protein name | Glutamate receptor Putative NMDtranscript(AltAcc_e11) Glutamate receptor ionotropic, kainate 4 (GluK4) (Excitatory amino acid receptor 1) (EAA1) (Glutamate receptor KA-1) (KA1) |
| Synonyms | GRIK |
| Description | FUNCTION: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. FUNCTION: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. . FUNCTION: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. . FUNCTION: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. . |
| Accessions | Q16099 ENST00000527524.8 ENST00000438375.2 A0A8D9UJ88 A6H8K8 A0A8D9PH79 A0A8D9PH78 ENST00000638419.1 |
