CTNND1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0099072Biological processregulation of postsynaptic membrane neurotransmitter receptor levels
GO_0090090Biological processnegative regulation of canonical Wnt signaling pathway
GO_0044331Biological processcell-cell adhesion mediated by cadherin
GO_0050821Biological processprotein stabilization
GO_0016055Biological processWnt signaling pathway
GO_0098609Biological processcell-cell adhesion
GO_0098978Cellular componentglutamatergic synapse
GO_0030496Cellular componentmidbody
GO_0005915Cellular componentzonula adherens
GO_0098685Cellular componentSchaffer collateral - CA1 synapse
GO_0005886Cellular componentplasma membrane
GO_0043197Cellular componentdendritic spine
GO_0070062Cellular componentextracellular exosome
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0016342Cellular componentcatenin complex
GO_0005911Cellular componentcell-cell junction
GO_0009986Cellular componentcell surface
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0030426Cellular componentgrowth cone
GO_0005737Cellular componentcytoplasm
GO_0030027Cellular componentlamellipodium
GO_0099092Cellular componentpostsynaptic density, intracellular component
GO_0098831Cellular componentpresynaptic active zone cytoplasmic component
GO_0005634Cellular componentnucleus
GO_0045296Molecular functioncadherin binding
GO_0005102Molecular functionsignaling receptor binding
GO_0008013Molecular functionbeta-catenin binding
GO_1990782Molecular functionprotein tyrosine kinase binding
GO_0140311Molecular functionprotein sequestering activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCTNND1
Protein nameCTNND1 protein
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Catenin delta 1
SynonymsKIAA0384
DescriptionFUNCTION: Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability . Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics . Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors . .

AccessionsENST00000399050.10 [O60716-1]
ENST00000426142.6 [O60716-21]
ENST00000533189.1
A0A669KB05
ENST00000683201.1
ENST00000682621.1
ENST00000531007.2
ENST00000532649.5 [O60716-13]
ENST00000531014.5 [O60716-26]
ENST00000529526.5 [O60716-13]
ENST00000526938.5 [O60716-7]
ENST00000530748.5 [O60716-11]
ENST00000532245.5 [O60716-21]
A0A804HIL4
ENST00000532787.5 [O60716-22]
ENST00000528232.5 [O60716-19]
ENST00000524630.5 [O60716-5]
ENST00000528621.5 [O60716-13]
E9PKL1
A0A669KB62
ENST00000361332.8 [O60716-2]
ENST00000673683.1 [O60716-5]
ENST00000529986.5 [O60716-21]
ENST00000529873.5 [O60716-14]
ENST00000530068.5
Q96FS1
E9PKY0
ENST00000534579.5 [O60716-13]
ENST00000527467.5 [O60716-25]
ENST00000533667.5 [O60716-30]
O60716
ENST00000361391.10 [O60716-6]
ENST00000361796.9 [O60716-3]
ENST00000530094.5 [O60716-18]
ENST00000532463.5 [O60716-21]
ENST00000674106.1
ENST00000532844.5 [O60716-9]
A0A804HJM1
ENST00000526357.5 [O60716-10]
ENST00000673826.1
A0A804HK15
C9JZR2
ENST00000529919.5
H0YC95
ENST00000674015.1
ENST00000358694.10 [O60716-5]
ENST00000526772.5 [O60716-29]
ENST00000525902.5 [O60716-27]
ENST00000683769.1
ENST00000415361.6 [O60716-17]
ENST00000428599.6 [O60716-5]