GO_0016055 | OmnibusX

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	DKK2-KREMEN2+LRP6	DKK2_HUMAN -	Ligand-Receptor	Signaling by WNT inhibition
2	DKK2-LRP6	DKK2_HUMAN - LRP6_HUMAN	Ligand-Receptor	Signaling by WNT
3	RSPO1-FZD8+LRP6	RSPO1_HUMAN -	Ligand-Receptor	Signaling by R-spondin
4	RSPO1-KREMEN1+LRP6	RSPO1_HUMAN -	Ligand-Receptor	Signaling by R-spondin
5	RSPO1-LGR4	RSPO1_HUMAN - LGR4_HUMAN	Ligand-Receptor	Signaling by R-spondin
6	RSPO1-LGR6	RSPO1_HUMAN - LGR6_HUMAN	Ligand-Receptor	Signaling by R-spondin
7	RSPO4-LGR4	RSPO4_HUMAN - LGR4_HUMAN	Ligand-Receptor	Signaling by R-spondin
8	RSPO4-LGR6	RSPO4_HUMAN - LGR6_HUMAN	Ligand-Receptor	Signaling by R-spondin
9	WNT1-FZD10+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
10	WNT1-FZD1+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
11	WNT1-FZD2+LRP5	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
12	WNT1-FZD2+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
13	WNT1-FZD3+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
14	WNT1-FZD4+LRP5	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
15	WNT1-FZD4+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
16	WNT1-FZD5+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
17	WNT1-FZD6+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
18	WNT1-FZD7+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
19	WNT1-FZD8+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
20	WNT1-FZD9+LRP6	WNT1_HUMAN -	Ligand-Receptor	Signaling by WNT
21	WNT1-WIF1	WNT1_HUMAN - WIF1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
22	WNT16-FZD10+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
23	WNT16-FZD1+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
24	WNT16-FZD2+LRP5	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
25	WNT16-FZD2+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
26	WNT16-FZD3+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
27	WNT16-FZD4+LRP5	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
28	WNT16-FZD4+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
29	WNT16-FZD5+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
30	WNT16-FZD6+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
31	WNT16-FZD7+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
32	WNT16-FZD8+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
33	WNT16-FZD9+LRP6	WNT16_HUMAN -	Ligand-Receptor	Signaling by WNT
34	WNT16-WIF1	WNT16_HUMAN - WIF1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
35	WNT5A-FZD10+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
36	WNT5A-FZD2+LRP5	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
37	WNT5A-FZD2+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
38	WNT5A-FZD3+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
39	WNT5A-FZD4+LRP5	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
40	WNT5A-FZD4+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
41	WNT5A-FZD5+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
42	WNT5A-FZD6+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
43	WNT5A-FZD7+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
44	WNT5A-FZD8+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
45	WNT5A-FZD9+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
46	WNT5A-ROR1	WNT5A_HUMAN - ROR1_HUMAN	Ligand-Receptor	Signaling by WNT
47	WNT5A-ROR2	WNT5A_HUMAN - ROR2_HUMAN	Ligand-Receptor	Signaling by WNT
48	WNT5A-WIF1	WNT5A_HUMAN - WIF1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition
49	WNT7B-FZD10+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
50	WNT7B-FZD1+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
51	WNT7B-FZD2+LRP5	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
52	WNT7B-FZD2+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
53	WNT7B-FZD3+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
54	WNT7B-FZD4+LRP5	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
55	WNT7B-FZD4+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
56	WNT7B-FZD5+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
57	WNT7B-FZD6+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
58	WNT7B-FZD7+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
59	WNT7B-FZD8+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
60	WNT7B-FZD9+LRP6	WNT7B_HUMAN -	Ligand-Receptor	Signaling by WNT
61	WNT7B-WIF1	WNT7B_HUMAN - WIF1_HUMAN	Ligand-Ligand	Signaling by WNT inhibition

Name	Wnt signaling pathway
ID	GO_0016055
collection_id	Biological process
Alternative ID	GO:0007222
Exact synonym	Wg signaling pathway, Wg signalling pathway, Wingless signaling pathway, Wingless signalling pathway, Wnt receptor signaling pathway, Wnt receptor signalling pathway, frizzled signaling pathway, frizzled signalling pathway
Description	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a target cell and ending with a change in cell state.
Related synonym	Wnt-activated signaling pathway
External URL
Genes	CTNND2 CPE ETV2 DLX3 GPC4 WWOX PRKAA1 NKD2 DACT1 AMER2 TMEM131L SENP2 DAAM2 CCAR2 DRAXIN CELSR2 CDK14 CUSTOS RAC3 PRKAA2 CUL3 APCDD1 URS0000472EB8_9606 DAB2 TLE2 MARK1 SHISA6 TLE3 LMBR1L FERMT2 LRRFIP2 OTULIN LGR4 TNIK TGFB1I1 TNKS DDIT3 CCNY VAX2 CTNND1 CELA1 RTF1 BARX1 URS0000B922CB_9606 CCND1 ROR2 CPZ PAF1 CSNK1D BTRC MITF NDRG2 AMER1 WNT16 MACF1 LDB1 DKK2 LRP6 GSC LRP4 NKD1 CTR9 NPHP3 DKK4 HBP1 CSNK1G3 ZBTB33 CCNE1 GID8 URS00007E437B_9606 MBD2 AMFR NHERF1 WNT1 ZRANB1 AMER3 WIF1 FAM53B CSNK2A1 TLE1 RNF43 CTNNBIP1 CSNK2B UBAC2 SPIN1 XIAP MCC APC HMGXB4 RSPO4 EPM2A PORCN FZD4 FZD2 TLE5 GRK6 TLE4 DKK3 BRD7 RNF138 CD24 FBXW11 USP34 DDB1 TRABD2B GSK3A WNT5A SOX17 PLCG2 CSNK1A1L CSNK2A2 LGR6 URS0000184017_9606 VPS35 WNT7B MESD CYLD RNF146 KREMEN2 KREMEN1 HIC1 TMEM198 PIAS4 CCN4 TMEM88 SKIC8 DDX3X ZNRF3 PKD1 NOTUM LEO1 CSNK1G1 FBXW4 TNKS2 DRD2 CDC73 AMOTL2 TRABD2A GRK5 RSPO1 CHD8 CSNK1G2 PKD2 NXN FGF10 STRN AMOTL1 ZBED3 BCL7B APC2 MARK2 CSNK1A1 HHEX INVS ROR1 CALCOCO1 TAX1BP3 CXXC4 ARL6 TMEM170B KLHL12 LZTS2 WLS

Wnt signaling pathway

I. Involved cell-cell interactions

II. Literature review