ZBED3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZBED3 at tissue level.

III. Associated gene sets

GO_0009749Biological processresponse to glucose
GO_0090263Biological processpositive regulation of canonical Wnt signaling pathway
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0032868Biological processresponse to insulin
GO_0051643Biological processendoplasmic reticulum localization
GO_0051293Biological processestablishment of spindle localization
GO_0040019Biological processpositive regulation of embryonic development
GO_0001933Biological processnegative regulation of protein phosphorylation
GO_0050821Biological processprotein stabilization
GO_0007015Biological processactin filament organization
GO_0051646Biological processmitochondrion localization
GO_0016055Biological processWnt signaling pathway
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005615Cellular componentextracellular space
GO_0016020Cellular componentmembrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0000785Cellular componentchromatin
GO_0003677Molecular functionDNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZBED3
Protein nameZinc finger BED domain-containing protein 3 (Axin-interacting protein)
Zinc finger BED-type containing 3
Zinc finger, BED domain containing 3 variant (Zinc finger, BED-type containing 3, isoform CRA_a)
SynonymshCG_1646047
DescriptionFUNCTION: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin (By similarity). Involved in transcription activation of Wnt target gene expression (By similarity). Plays a role in symmetric division of blastomeres in the early stages of embryogenesis via regulation of mitotic spindle central positioning and organization of the F-actin filament network (By similarity). Plays a role in regulating the distribution of cellular organelles, via modulation of cytoskeletal dynamics and cytoplasmic lattice formation (By similarity). .

AccessionsQ53EL5
ENST00000511587.1
ENST00000255198.3
Q96IU2
D6RIC4