TMEM170B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090090Biological processnegative regulation of canonical Wnt signaling pathway
GO_0016055Biological processWnt signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTMEM170B
Protein nameTransmembrane protein 170B
Synonyms
DescriptionFUNCTION: Negatively regulates the canonical Wnt signaling in breast cancer cells. Exerts an inhibitory effect on breast cancer growth by inhibiting CTNNB1 stabilization and nucleus translocation, which reduces the activity of Wnt targets . .

AccessionsQ5T4T1
ENST00000379426.2