Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 7 studies | 25% ± 6% | |
B cell | 6 studies | 24% ± 8% | |
natural killer cell | 6 studies | 24% ± 8% | |
endothelial cell | 6 studies | 21% ± 5% | |
epithelial cell | 6 studies | 30% ± 14% | |
non-classical monocyte | 4 studies | 35% ± 18% | |
CD8-positive, alpha-beta T cell | 4 studies | 27% ± 7% | |
leukocyte | 3 studies | 19% ± 3% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 25% ± 5% | |
classical monocyte | 3 studies | 33% ± 12% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 31% ± 6% | |
mature NK T cell | 3 studies | 21% ± 4% | |
microglial cell | 3 studies | 20% ± 3% | |
squamous epithelial cell | 3 studies | 28% ± 15% | |
basal cell | 3 studies | 25% ± 5% | |
gamma-delta T cell | 3 studies | 29% ± 4% | |
transit amplifying cell | 3 studies | 22% ± 4% | |
plasmacytoid dendritic cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4824.32 | 1445 / 1445 | 100% | 71.20 | 183 / 183 |
pancreas | 100% | 3001.63 | 328 / 328 | 100% | 65.45 | 178 / 178 |
thymus | 100% | 5135.68 | 653 / 653 | 100% | 55.61 | 604 / 605 |
uterus | 100% | 4824.69 | 170 / 170 | 100% | 75.28 | 458 / 459 |
ovary | 100% | 4954.06 | 180 / 180 | 100% | 57.03 | 429 / 430 |
stomach | 100% | 3694.90 | 359 / 359 | 100% | 67.95 | 285 / 286 |
brain | 100% | 4922.77 | 2632 / 2642 | 100% | 49.14 | 705 / 705 |
intestine | 100% | 4874.42 | 966 / 966 | 100% | 71.28 | 525 / 527 |
adrenal gland | 100% | 6505.48 | 258 / 258 | 100% | 60.19 | 229 / 230 |
skin | 100% | 5425.12 | 1809 / 1809 | 99% | 82.03 | 469 / 472 |
kidney | 100% | 5146.67 | 89 / 89 | 99% | 47.20 | 894 / 901 |
bladder | 100% | 4285.00 | 21 / 21 | 99% | 76.77 | 500 / 504 |
prostate | 100% | 5800.16 | 245 / 245 | 99% | 58.34 | 498 / 502 |
lung | 100% | 6853.18 | 577 / 578 | 99% | 62.78 | 1147 / 1155 |
breast | 100% | 5299.09 | 459 / 459 | 99% | 54.39 | 1108 / 1118 |
liver | 100% | 2893.54 | 226 / 226 | 98% | 36.19 | 398 / 406 |
adipose | 100% | 4886.40 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 64.99 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 76.09 | 29 / 29 |
spleen | 100% | 9220.76 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 91.86 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 45.15 | 1 / 1 |
blood vessel | 100% | 3880.56 | 1332 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2969.16 | 799 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 7959.15 | 924 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 2744.40 | 847 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0030148 | Biological process | sphingolipid biosynthetic process |
GO_0018105 | Biological process | peptidyl-serine phosphorylation |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0006468 | Biological process | protein phosphorylation |
GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
GO_0006897 | Biological process | endocytosis |
GO_0005829 | Cellular component | cytosol |
GO_0005938 | Cellular component | cell cortex |
GO_0016020 | Cellular component | membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | CSNK1G2 |
Protein name | Casein kinase I isoform gamma-2 (CKI-gamma 2) (EC 2.7.11.1) non-specific serine/threonine protein kinase (EC 2.7.11.1) Casein kinase 1 gamma 2 |
Synonyms | CK1G2 |
Description | FUNCTION: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation . Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate (By similarity). Involved in regulation of reactive oxygen species (ROS) levels . . |
Accessions | P78368 K7EP38 ENST00000255641.13 ENST00000585959.2 K7ESB6 ENST00000591002.5 ENST00000589350.2 A0A087WXD7 A0A087WW97 K7EJC0 ENST00000591752.5 ENST00000589385.5 A0A087WZK4 A0A087WWF5 ENST00000615564.1 ENST00000585957.2 |