Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 20 studies | 24% ± 8% | |
endothelial cell | 17 studies | 29% ± 12% | |
smooth muscle cell | 16 studies | 27% ± 10% | |
B cell | 15 studies | 24% ± 8% | |
endothelial cell of lymphatic vessel | 13 studies | 31% ± 9% | |
astrocyte | 11 studies | 42% ± 14% | |
natural killer cell | 10 studies | 23% ± 9% | |
adipocyte | 9 studies | 45% ± 6% | |
fibroblast | 8 studies | 22% ± 7% | |
CD16-positive, CD56-dim natural killer cell, human | 7 studies | 20% ± 4% | |
CD16-negative, CD56-bright natural killer cell, human | 6 studies | 24% ± 7% | |
memory B cell | 6 studies | 21% ± 6% | |
naive B cell | 6 studies | 26% ± 10% | |
abnormal cell | 5 studies | 28% ± 5% | |
epithelial cell | 5 studies | 44% ± 21% | |
myofibroblast cell | 5 studies | 22% ± 5% | |
oligodendrocyte precursor cell | 4 studies | 19% ± 5% | |
mucosal invariant T cell | 4 studies | 29% ± 9% | |
connective tissue cell | 4 studies | 27% ± 3% | |
plasma cell | 4 studies | 27% ± 6% | |
retinal cone cell | 4 studies | 19% ± 4% | |
hepatocyte | 4 studies | 60% ± 21% | |
GABAergic neuron | 4 studies | 28% ± 2% | |
glutamatergic neuron | 4 studies | 44% ± 12% | |
neuron | 4 studies | 39% ± 13% | |
plasmablast | 3 studies | 18% ± 1% | |
glial cell | 3 studies | 25% ± 8% | |
precursor B cell | 3 studies | 30% ± 12% | |
immature B cell | 3 studies | 26% ± 5% | |
lymphocyte | 3 studies | 19% ± 3% | |
innate lymphoid cell | 3 studies | 31% ± 18% | |
endothelial cell of vascular tree | 3 studies | 28% ± 9% | |
muscle cell | 3 studies | 23% ± 4% | |
group 3 innate lymphoid cell | 3 studies | 32% ± 17% | |
Schwann cell | 3 studies | 23% ± 5% | |
melanocyte | 3 studies | 25% ± 6% | |
transit amplifying cell | 3 studies | 30% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 4597.39 | 180 / 180 | 100% | 61.07 | 430 / 430 |
prostate | 100% | 3877.85 | 245 / 245 | 99% | 48.80 | 499 / 502 |
liver | 100% | 4103.81 | 226 / 226 | 99% | 49.75 | 403 / 406 |
brain | 100% | 2975.46 | 2632 / 2642 | 99% | 42.39 | 701 / 705 |
stomach | 100% | 3623.20 | 359 / 359 | 98% | 31.33 | 279 / 286 |
esophagus | 100% | 3284.34 | 1445 / 1445 | 97% | 36.23 | 178 / 183 |
pancreas | 99% | 2753.46 | 325 / 328 | 98% | 30.87 | 174 / 178 |
intestine | 100% | 4309.93 | 966 / 966 | 97% | 30.10 | 510 / 527 |
adrenal gland | 100% | 3805.53 | 258 / 258 | 97% | 41.77 | 222 / 230 |
lung | 99% | 2667.71 | 575 / 578 | 95% | 23.97 | 1100 / 1155 |
uterus | 100% | 6441.24 | 170 / 170 | 94% | 34.75 | 432 / 459 |
kidney | 98% | 2069.11 | 87 / 89 | 95% | 24.30 | 858 / 901 |
bladder | 100% | 3683.71 | 21 / 21 | 91% | 25.24 | 457 / 504 |
breast | 100% | 4723.35 | 459 / 459 | 89% | 28.69 | 994 / 1118 |
skin | 87% | 2542.52 | 1574 / 1809 | 92% | 35.22 | 435 / 472 |
thymus | 100% | 3293.88 | 652 / 653 | 73% | 13.15 | 439 / 605 |
adipose | 100% | 4869.07 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4092.65 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 5489.11 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.68 | 1 / 1 |
muscle | 100% | 4348.91 | 802 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 23.33 | 44 / 45 |
heart | 93% | 1286.89 | 804 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 75% | 14.44 | 60 / 80 |
peripheral blood | 37% | 396.00 | 342 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 11.50 | 10 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0030178 | Biological process | negative regulation of Wnt signaling pathway |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_2000811 | Biological process | negative regulation of anoikis |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
GO_0043124 | Biological process | negative regulation of canonical NF-kappaB signal transduction |
GO_1990907 | Cellular component | beta-catenin-TCF complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005667 | Cellular component | transcription regulator complex |
GO_0005634 | Cellular component | nucleus |
GO_0140297 | Molecular function | DNA-binding transcription factor binding |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TLE1 |
Protein name | TLE family member 1, transcriptional corepressor Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1) |
Synonyms | |
Description | FUNCTION: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity). The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. . |
Accessions | ENST00000674113.1 Q5T3G3 A0A669KBB1 ENST00000418319.5 ENST00000464999.1 Q5T3G2 ENST00000491534.5 ENST00000376484.2 ENST00000376463.3 ENST00000376499.8 A0A669KAE5 F6T2C8 A0A669KBK8 Q04724 |