Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 14 studies | 32% ± 15% | |
oligodendrocyte precursor cell | 11 studies | 42% ± 19% | |
endothelial cell | 9 studies | 28% ± 11% | |
adipocyte | 8 studies | 32% ± 10% | |
fibroblast | 8 studies | 28% ± 16% | |
neuron | 4 studies | 28% ± 14% | |
connective tissue cell | 4 studies | 25% ± 6% | |
pericyte | 4 studies | 18% ± 3% | |
capillary endothelial cell | 3 studies | 24% ± 3% | |
adventitial cell | 3 studies | 21% ± 2% |
Insufficient scRNA-seq data for expression of APCDD1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 99% | 6597.78 | 243 / 245 | 98% | 43.46 | 491 / 502 |
brain | 92% | 3129.01 | 2439 / 2642 | 100% | 75.76 | 702 / 705 |
ovary | 98% | 5444.43 | 176 / 180 | 91% | 31.94 | 390 / 430 |
uterus | 98% | 5856.31 | 166 / 170 | 84% | 34.43 | 387 / 459 |
bladder | 100% | 6924.71 | 21 / 21 | 76% | 34.92 | 382 / 504 |
esophagus | 98% | 3900.35 | 1414 / 1445 | 74% | 27.77 | 136 / 183 |
intestine | 89% | 2372.85 | 858 / 966 | 76% | 51.29 | 398 / 527 |
breast | 97% | 6227.63 | 444 / 459 | 65% | 11.71 | 730 / 1118 |
stomach | 91% | 3951.71 | 326 / 359 | 71% | 51.72 | 202 / 286 |
lung | 83% | 2572.47 | 481 / 578 | 61% | 15.49 | 709 / 1155 |
skin | 84% | 11543.69 | 1515 / 1809 | 46% | 32.80 | 218 / 472 |
pancreas | 36% | 580.87 | 118 / 328 | 91% | 28.69 | 162 / 178 |
adrenal gland | 81% | 2188.21 | 209 / 258 | 35% | 12.06 | 80 / 230 |
adipose | 95% | 6058.46 | 1147 / 1204 | 0% | 0 | 0 / 0 |
heart | 89% | 3098.37 | 770 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 84% | 22.38 | 38 / 45 |
blood vessel | 79% | 3059.18 | 1053 / 1335 | 0% | 0 | 0 / 0 |
thymus | 43% | 745.24 | 282 / 653 | 34% | 4.36 | 206 / 605 |
kidney | 29% | 664.09 | 26 / 89 | 38% | 5.72 | 343 / 901 |
spleen | 27% | 384.04 | 66 / 241 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 18% | 10.36 | 72 / 406 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.61 | 2 / 29 |
muscle | 4% | 43.81 | 29 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.12 | 1 / 80 |
peripheral blood | 1% | 12.31 | 6 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043615 | Biological process | astrocyte cell migration |
GO_0030178 | Biological process | negative regulation of Wnt signaling pathway |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0042487 | Biological process | regulation of odontogenesis of dentin-containing tooth |
GO_0001942 | Biological process | hair follicle development |
GO_0005886 | Cellular component | plasma membrane |
GO_0017147 | Molecular function | Wnt-protein binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | APCDD1 |
Protein name | Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein) Protein APCDD1 APC down-regulated 1 |
Synonyms | DRAPC1 FP7019 |
Description | FUNCTION: Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis. . |
Accessions | ENST00000578882.1 ENST00000579685.1 X6RH63 ENST00000355285.10 J3KTQ6 J3QSE3 Q8J025 ENST00000423585.2 ENST00000582723.1 ENST00000584596.2 J3KTR1 V9GY82 |