APCDD1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of APCDD1 at tissue level.

III. Associated gene sets

GO_0043615Biological processastrocyte cell migration
GO_0030178Biological processnegative regulation of Wnt signaling pathway
GO_0016055Biological processWnt signaling pathway
GO_0042487Biological processregulation of odontogenesis of dentin-containing tooth
GO_0001942Biological processhair follicle development
GO_0005886Cellular componentplasma membrane
GO_0017147Molecular functionWnt-protein binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAPCDD1
Protein nameProtein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein)
Protein APCDD1
APC down-regulated 1
SynonymsDRAPC1
FP7019
DescriptionFUNCTION: Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis. .

AccessionsENST00000578882.1
ENST00000579685.1
X6RH63
ENST00000355285.10
J3KTQ6
J3QSE3
Q8J025
ENST00000423585.2
ENST00000582723.1
ENST00000584596.2
J3KTR1
V9GY82