Insufficient scRNA-seq data for expression of CPZ at single-cell level.
Insufficient scRNA-seq data for expression of CPZ at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 39.90 | 21 / 21 | 20% | 0.60 | 101 / 504 |
ovary | 100% | 697.32 | 180 / 180 | 17% | 0.32 | 72 / 430 |
uterus | 96% | 54.46 | 163 / 170 | 9% | 0.27 | 41 / 459 |
thymus | 95% | 32.40 | 623 / 653 | 6% | 0.12 | 36 / 605 |
ureter | 0% | 0 | 0 / 0 | 100% | 15.03 | 1 / 1 |
lung | 87% | 24.70 | 505 / 578 | 2% | 0.04 | 25 / 1155 |
breast | 85% | 41.86 | 392 / 459 | 2% | 0.03 | 22 / 1118 |
prostate | 78% | 19.93 | 191 / 245 | 0% | 0 | 0 / 502 |
adipose | 73% | 24.46 | 880 / 1204 | 0% | 0 | 0 / 0 |
esophagus | 67% | 28.43 | 969 / 1445 | 4% | 0.04 | 7 / 183 |
skin | 69% | 23.02 | 1251 / 1809 | 0% | 0.01 | 2 / 472 |
intestine | 56% | 10.25 | 544 / 966 | 5% | 0.11 | 26 / 527 |
stomach | 42% | 8.51 | 151 / 359 | 4% | 0.05 | 11 / 286 |
adrenal gland | 37% | 4.61 | 95 / 258 | 1% | 0.01 | 2 / 230 |
blood vessel | 34% | 4.71 | 456 / 1335 | 0% | 0 | 0 / 0 |
kidney | 30% | 5.22 | 27 / 89 | 1% | 0.02 | 5 / 901 |
spleen | 29% | 3.39 | 70 / 241 | 0% | 0 | 0 / 0 |
heart | 22% | 3.16 | 190 / 861 | 0% | 0 | 0 / 0 |
pancreas | 9% | 0.98 | 31 / 328 | 9% | 0.15 | 16 / 178 |
liver | 8% | 0.73 | 18 / 226 | 0% | 0.01 | 2 / 406 |
brain | 5% | 0.54 | 124 / 2642 | 0% | 0.01 | 3 / 705 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.02 | 1 / 45 |
muscle | 1% | 0.10 | 9 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.01 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006518 | Biological process | peptide metabolic process |
GO_0016485 | Biological process | protein processing |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0006508 | Biological process | proteolysis |
GO_0005615 | Cellular component | extracellular space |
GO_0008270 | Molecular function | zinc ion binding |
GO_0004181 | Molecular function | metallocarboxypeptidase activity |
Gene name | CPZ |
Protein name | Carboxypeptidase Z, isoform CRA_b (Epididymis secretory sperm binding protein) Carboxypeptidase Z Carboxypeptidase Z (CPZ) (EC 3.4.17.-) |
Synonyms | hCG_16447 |
Description | FUNCTION: Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. . |
Accessions | ENST00000315782.6 [Q66K79-2] D6RBI5 ENST00000382480.6 [Q66K79-3] ENST00000360986.9 [Q66K79-1] A0A384MDV6 Q66K79 ENST00000515606.1 |