FGF10 | OmnibusX

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FGF10 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	1314.05	457 / 459	64%	19.13	715 / 1118
prostate	94%	428.65	230 / 245	66%	1.91	331 / 502
pancreas	98%	220.50	323 / 328	53%	1.90	95 / 178
thymus	97%	492.56	632 / 653	13%	1.08	81 / 605
bladder	95%	425.43	20 / 21	14%	0.52	69 / 504
intestine	87%	403.46	838 / 966	21%	0.64	111 / 527
ovary	98%	629.64	176 / 180	3%	0.18	14 / 430
lung	87%	223.01	501 / 578	14%	0.90	160 / 1155
adipose	100%	853.95	1201 / 1204	0%	0	0 / 0
uterus	81%	317.24	138 / 170	17%	1.02	76 / 459
esophagus	73%	160.12	1058 / 1445	18%	0.36	33 / 183
stomach	58%	309.41	209 / 359	33%	1.42	94 / 286
blood vessel	80%	232.18	1070 / 1335	0%	0	0 / 0
adrenal gland	14%	15.35	35 / 258	37%	4.37	85 / 230
skin	23%	34.88	425 / 1809	7%	0.55	35 / 472
kidney	16%	22.75	14 / 89	2%	0.09	18 / 901
heart	13%	17.71	115 / 861	0%	0	0 / 0
brain	2%	3.48	60 / 2642	7%	0.34	49 / 705
muscle	8%	10.74	66 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	7%	0.15	3 / 45
liver	0%	0	0 / 226	2%	0.12	8 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0061115	Biological process	lung proximal/distal axis specification
GO_0060054	Biological process	positive regulation of epithelial cell proliferation involved in wound healing
GO_0048807	Biological process	female genitalia morphogenesis
GO_0048146	Biological process	positive regulation of fibroblast proliferation
GO_0001974	Biological process	blood vessel remodeling
GO_0001759	Biological process	organ induction
GO_0030916	Biological process	otic vesicle formation
GO_0060510	Biological process	type II pneumocyte differentiation
GO_0060661	Biological process	submandibular salivary gland formation
GO_0050918	Biological process	positive chemotaxis
GO_0001656	Biological process	metanephros development
GO_0032808	Biological process	lacrimal gland development
GO_0050677	Biological process	positive regulation of urothelial cell proliferation
GO_0070352	Biological process	positive regulation of white fat cell proliferation
GO_0061033	Biological process	secretion by lung epithelial cell involved in lung growth
GO_0060915	Biological process	mesenchymal cell differentiation involved in lung development
GO_0030878	Biological process	thyroid gland development
GO_0010838	Biological process	positive regulation of keratinocyte proliferation
GO_0070343	Biological process	white fat cell proliferation
GO_2000647	Biological process	negative regulation of stem cell proliferation
GO_1900087	Biological process	positive regulation of G1/S transition of mitotic cell cycle
GO_0071338	Biological process	positive regulation of hair follicle cell proliferation
GO_1902178	Biological process	fibroblast growth factor receptor apoptotic signaling pathway
GO_0030538	Biological process	embryonic genitalia morphogenesis
GO_0030857	Biological process	negative regulation of epithelial cell differentiation
GO_0030036	Biological process	actin cytoskeleton organization
GO_0060447	Biological process	bud outgrowth involved in lung branching
GO_0060667	Biological process	branch elongation involved in salivary gland morphogenesis
GO_0051549	Biological process	positive regulation of keratinocyte migration
GO_0030334	Biological process	regulation of cell migration
GO_0097192	Biological process	extrinsic apoptotic signaling pathway in absence of ligand
GO_0060615	Biological process	mammary gland bud formation
GO_0046579	Biological process	positive regulation of Ras protein signal transduction
GO_0070374	Biological process	positive regulation of ERK1 and ERK2 cascade
GO_0043616	Biological process	keratinocyte proliferation
GO_0050872	Biological process	white fat cell differentiation
GO_0042475	Biological process	odontogenesis of dentin-containing tooth
GO_0050673	Biological process	epithelial cell proliferation
GO_0072089	Biological process	stem cell proliferation
GO_0060665	Biological process	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO_0060496	Biological process	mesenchymal-epithelial cell signaling involved in lung development
GO_0001525	Biological process	angiogenesis
GO_0007431	Biological process	salivary gland development
GO_0007368	Biological process	determination of left/right symmetry
GO_0010628	Biological process	positive regulation of gene expression
GO_0048808	Biological process	male genitalia morphogenesis
GO_0060430	Biological process	lung saccule development
GO_0000132	Biological process	establishment of mitotic spindle orientation
GO_0046877	Biological process	regulation of saliva secretion
GO_0003338	Biological process	metanephros morphogenesis
GO_0042693	Biological process	muscle cell fate commitment
GO_0042060	Biological process	wound healing
GO_0001823	Biological process	mesonephros development
GO_0050679	Biological process	positive regulation of epithelial cell proliferation
GO_0070371	Biological process	ERK1 and ERK2 cascade
GO_0050674	Biological process	urothelial cell proliferation
GO_0050671	Biological process	positive regulation of lymphocyte proliferation
GO_0048144	Biological process	fibroblast proliferation
GO_0031076	Biological process	embryonic camera-type eye development
GO_0030949	Biological process	positive regulation of vascular endothelial growth factor receptor signaling pathway
GO_0008543	Biological process	fibroblast growth factor receptor signaling pathway
GO_0032355	Biological process	response to estradiol
GO_0060664	Biological process	epithelial cell proliferation involved in salivary gland morphogenesis
GO_0031016	Biological process	pancreas development
GO_0090263	Biological process	positive regulation of canonical Wnt signaling pathway
GO_0045739	Biological process	positive regulation of DNA repair
GO_0009887	Biological process	animal organ morphogenesis
GO_0031069	Biological process	hair follicle morphogenesis
GO_0060513	Biological process	prostatic bud formation
GO_0001934	Biological process	positive regulation of protein phosphorylation
GO_0060174	Biological process	limb bud formation
GO_0042246	Biological process	tissue regeneration
GO_0060879	Biological process	semicircular canal fusion
GO_0048538	Biological process	thymus development
GO_0070384	Biological process	Harderian gland development
GO_0048010	Biological process	vascular endothelial growth factor receptor signaling pathway
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0060595	Biological process	fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO_0016055	Biological process	Wnt signaling pathway
GO_0050930	Biological process	induction of positive chemotaxis
GO_0010634	Biological process	positive regulation of epithelial cell migration
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0035019	Biological process	somatic stem cell population maintenance
GO_0008589	Biological process	regulation of smoothened signaling pathway
GO_0032781	Biological process	positive regulation of ATP-dependent activity
GO_0070075	Biological process	tear secretion
GO_0032925	Biological process	regulation of activin receptor signaling pathway
GO_0048754	Biological process	branching morphogenesis of an epithelial tube
GO_0060019	Biological process	radial glial cell differentiation
GO_0060449	Biological process	bud elongation involved in lung branching
GO_2000648	Biological process	positive regulation of stem cell proliferation
GO_0043410	Biological process	positive regulation of MAPK cascade
GO_0034394	Biological process	protein localization to cell surface
GO_0048536	Biological process	spleen development
GO_0009880	Biological process	embryonic pattern specification
GO_0050731	Biological process	positive regulation of peptidyl-tyrosine phosphorylation
GO_0001938	Biological process	positive regulation of endothelial cell proliferation
GO_0030154	Biological process	cell differentiation
GO_0048557	Biological process	embryonic digestive tract morphogenesis
GO_0001935	Biological process	endothelial cell proliferation
GO_0051145	Biological process	smooth muscle cell differentiation
GO_0060428	Biological process	lung epithelium development
GO_0060436	Biological process	bronchiole morphogenesis
GO_2001240	Biological process	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO_0021983	Biological process	pituitary gland development
GO_0045747	Biological process	positive regulation of Notch signaling pathway
GO_0032496	Biological process	response to lipopolysaccharide
GO_0009986	Cellular component	cell surface
GO_0005634	Cellular component	nucleus
GO_0005576	Cellular component	extracellular region
GO_0005615	Cellular component	extracellular space
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0042056	Molecular function	chemoattractant activity
GO_0008201	Molecular function	heparin binding
GO_0005515	Molecular function	protein binding
GO_0008083	Molecular function	growth factor activity
GO_0005104	Molecular function	fibroblast growth factor receptor binding
GO_0005111	Molecular function	type 2 fibroblast growth factor receptor binding

Gene name	FGF10
Protein name	Fibroblast growth factor (FGF) Fibroblast growth factor 10 (FGF-10) (Keratinocyte growth factor 2) Fibroblast growth factor 10
Synonyms
Description	FUNCTION: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing. .
Accessions	ENST00000264664.5 ENST00000513107.1 O15520 D6RG33 Q8NFI9

FGF10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review