AMOTL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001525Biological processangiogenesis
GO_0030036Biological processactin cytoskeleton organization
GO_0016055Biological processWnt signaling pathway
GO_0030334Biological processregulation of cell migration
GO_0035329Biological processhippo signaling
GO_0003365Biological processestablishment of cell polarity involved in ameboidal cell migration
GO_0008180Cellular componentCOP9 signalosome
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0005923Cellular componentbicellular tight junction
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAMOTL1
Protein nameAngiomotin like 1
Angiomotin-like protein 1
Synonyms
DescriptionFUNCTION: Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. .

AccessionsENST00000317829.12 [Q8IY63-2]
F8WDH4
ENST00000299004.13
Q8IY63
ENST00000433060.3 [Q8IY63-1]