| Name | hippo signaling |
| ID | GO_0035329 |
| collection_id | Biological process |
| Exact synonym | hippo signal transduction, hippo signaling pathway |
| Description | An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation. |
| Related synonym | hippo signaling cascade, hippo signalling cascade |
| External URL | |
| Genes |