Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 18 studies | 36% ± 17% | |
| oligodendrocyte | 17 studies | 53% ± 20% | |
| GABAergic neuron | 6 studies | 24% ± 7% | |
| oligodendrocyte precursor cell | 6 studies | 25% ± 11% | |
| retina horizontal cell | 4 studies | 28% ± 10% | |
| retinal cone cell | 4 studies | 23% ± 5% | |
| Mueller cell | 4 studies | 42% ± 11% | |
| glutamatergic neuron | 4 studies | 30% ± 10% | |
| interneuron | 4 studies | 24% ± 7% | |
| neuron | 3 studies | 29% ± 17% | |
| retinal bipolar neuron | 3 studies | 21% ± 3% | |
| retinal rod cell | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 9378.80 | 2642 / 2642 | 99% | 60.38 | 695 / 705 |
| eye | 0% | 0 | 0 / 0 | 26% | 2.03 | 21 / 80 |
| adrenal gland | 0% | 6.83 | 1 / 258 | 19% | 0.70 | 44 / 230 |
| skin | 0% | 0 | 0 / 1809 | 4% | 0.25 | 17 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.64 | 1 / 29 |
| breast | 0% | 0 | 0 / 459 | 2% | 0.14 | 20 / 1118 |
| pancreas | 0% | 0 | 0 / 328 | 2% | 0.07 | 3 / 178 |
| adipose | 1% | 18.72 | 18 / 1204 | 0% | 0 | 0 / 0 |
| lung | 0% | 3.89 | 2 / 578 | 1% | 0.07 | 10 / 1155 |
| thymus | 0% | 0 | 0 / 653 | 1% | 0.06 | 5 / 605 |
| bladder | 0% | 0 | 0 / 21 | 1% | 0.06 | 4 / 504 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.03 | 7 / 901 |
| uterus | 0% | 0 | 0 / 170 | 0% | 0.02 | 2 / 459 |
| intestine | 0% | 0 | 0 / 966 | 0% | 0.01 | 1 / 527 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| esophagus | 0% | 0 | 0 / 1445 | 0% | 0 | 0 / 183 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0 | 0 / 502 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| stomach | 0% | 0 | 0 / 359 | 0% | 0 | 0 / 286 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016055 | Biological process | Wnt signaling pathway |
| GO_0060828 | Biological process | regulation of canonical Wnt signaling pathway |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0007398 | Biological process | ectoderm development |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
| GO_0008013 | Molecular function | beta-catenin binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | AMER2 |
| Protein name | APC membrane recruitment protein 2 (Amer2) (Protein FAM123A) |
| Synonyms | FAM123A |
| Description | FUNCTION: Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. . |
| Accessions | ENST00000515384.2 [Q8N7J2-1] Q8N7J2 ENST00000357816.2 [Q8N7J2-2] |