TAX1BP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030178Biological processnegative regulation of Wnt signaling pathway
GO_0007266Biological processRho protein signal transduction
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0016055Biological processWnt signaling pathway
GO_2000009Biological processnegative regulation of protein localization to cell surface
GO_0090630Biological processactivation of GTPase activity
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0015629Cellular componentactin cytoskeleton
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0001650Cellular componentfibrillar center
GO_0008013Molecular functionbeta-catenin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTAX1BP3
Protein nameTax1 binding protein 3
Tax1-binding protein 3 (Glutaminase-interacting protein 3) (Tax interaction protein 1) (TIP-1) (Tax-interacting protein 1)
SynonymsTIP1
DescriptionFUNCTION: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. .

AccessionsENST00000225525.4
A0A087X282
O14907
ENST00000611779.4