HBP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016055Biological processWnt signaling pathway
GO_0051726Biological processregulation of cell cycle
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003723Molecular functionRNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHBP1
Protein nameHMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)
HMG-box transcription factor 1
Synonyms
DescriptionFUNCTION: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. .

AccessionsENST00000638893.1 [O60381-1]
ENST00000222574.9 [O60381-1]
C9JPK6
ENST00000468410.5 [O60381-1]
ENST00000498408.1
ENST00000485846.5 [O60381-1]
ENST00000638303.2 [O60381-1]
C9JAW1
C9J5U3
ENST00000464009.1
U3KQE5
ENST00000478930.5
ENST00000468401.1
C9JQU7
H7C574
C9J8V6
ENST00000607681.1
ENST00000640195.1 [O60381-1]
O60381
ENST00000497535.5
ENST00000463790.1
H7C4S2
ENST00000479011.1