Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 23 studies | 37% ± 16% | |
endothelial cell of lymphatic vessel | 16 studies | 46% ± 23% | |
smooth muscle cell | 11 studies | 24% ± 8% | |
pericyte | 10 studies | 29% ± 13% | |
type I pneumocyte | 9 studies | 43% ± 20% | |
fibroblast | 8 studies | 26% ± 11% | |
vein endothelial cell | 7 studies | 40% ± 22% | |
ciliated cell | 7 studies | 27% ± 11% | |
basal cell | 7 studies | 44% ± 23% | |
astrocyte | 6 studies | 27% ± 9% | |
microglial cell | 6 studies | 33% ± 13% | |
epithelial cell | 6 studies | 39% ± 17% | |
type II pneumocyte | 5 studies | 24% ± 4% | |
glutamatergic neuron | 4 studies | 29% ± 13% | |
interneuron | 4 studies | 34% ± 7% | |
neuron | 4 studies | 29% ± 9% | |
retinal rod cell | 4 studies | 31% ± 8% | |
club cell | 4 studies | 38% ± 10% | |
endothelial cell of artery | 4 studies | 29% ± 12% | |
oligodendrocyte precursor cell | 3 studies | 24% ± 3% | |
capillary endothelial cell | 3 studies | 32% ± 10% | |
endothelial cell of vascular tree | 3 studies | 44% ± 12% | |
connective tissue cell | 3 studies | 26% ± 2% | |
myofibroblast cell | 3 studies | 39% ± 14% | |
muscle cell | 3 studies | 29% ± 9% | |
GABAergic neuron | 3 studies | 32% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 5496.87 | 245 / 245 | 100% | 50.30 | 502 / 502 |
ovary | 97% | 1886.14 | 175 / 180 | 99% | 55.36 | 425 / 430 |
pancreas | 100% | 2380.68 | 328 / 328 | 95% | 33.09 | 169 / 178 |
lung | 100% | 3371.39 | 577 / 578 | 95% | 37.67 | 1092 / 1155 |
uterus | 100% | 6193.28 | 170 / 170 | 94% | 50.25 | 431 / 459 |
thymus | 99% | 1886.30 | 648 / 653 | 94% | 42.36 | 568 / 605 |
esophagus | 100% | 3649.69 | 1445 / 1445 | 89% | 39.01 | 162 / 183 |
breast | 100% | 2708.66 | 457 / 459 | 84% | 20.55 | 941 / 1118 |
bladder | 100% | 5836.33 | 21 / 21 | 75% | 26.26 | 377 / 504 |
skin | 100% | 3632.68 | 1808 / 1809 | 74% | 18.32 | 348 / 472 |
brain | 82% | 869.38 | 2159 / 2642 | 90% | 16.96 | 632 / 705 |
stomach | 100% | 3193.49 | 358 / 359 | 62% | 12.94 | 176 / 286 |
kidney | 87% | 1232.03 | 77 / 89 | 65% | 13.40 | 585 / 901 |
intestine | 93% | 5865.61 | 898 / 966 | 52% | 10.33 | 275 / 527 |
adrenal gland | 75% | 831.60 | 193 / 258 | 41% | 6.78 | 95 / 230 |
muscle | 100% | 7290.56 | 803 / 803 | 0% | 0 | 0 / 0 |
adipose | 99% | 2245.88 | 1196 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 2405.13 | 1322 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 62.37 | 44 / 45 |
heart | 95% | 1214.29 | 817 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 85% | 14.05 | 68 / 80 |
liver | 51% | 454.65 | 115 / 226 | 31% | 6.82 | 127 / 406 |
spleen | 78% | 757.05 | 189 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 38% | 4.71 | 11 / 29 |
peripheral blood | 1% | 7.28 | 7 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030178 | Biological process | negative regulation of Wnt signaling pathway |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0031397 | Biological process | negative regulation of protein ubiquitination |
GO_0072359 | Biological process | circulatory system development |
GO_0030154 | Biological process | cell differentiation |
GO_0098869 | Biological process | cellular oxidant detoxification |
GO_0001701 | Biological process | in utero embryonic development |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0004791 | Molecular function | thioredoxin-disulfide reductase (NADPH) activity |
Gene name | NXN |
Protein name | Nucleoredoxin (EC 1.8.1.8) Nucleoredoxin |
Synonyms | NRX |
Description | FUNCTION: Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). . |
Accessions | ENST00000575801.5 [Q6DKJ4-3] ENST00000336868.8 [Q6DKJ4-1] ENST00000628478.1 A0A0G2JQK5 ENST00000627182.1 ENST00000537628.6 ENST00000571684.5 A0A0C4DGI2 Q6DKJ4 I3L4V6 |