FBXW4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0031146Biological processSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO_0016055Biological processWnt signaling pathway
GO_0030326Biological processembryonic limb morphogenesis
GO_0019005Cellular componentSCF ubiquitin ligase complex
GO_0000151Cellular componentubiquitin ligase complex
GO_0005829Cellular componentcytosol
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFBXW4
Protein nameF-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)
F-box and WD repeat domain containing 4
SynonymsFBW4
SHFM3
DescriptionFUNCTION: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.

AccessionsP57775
ENST00000664783.1
A0A5F9UQ55
ENST00000331272.9