Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 10 studies | 28% ± 10% | |
microglial cell | 9 studies | 28% ± 9% | |
astrocyte | 9 studies | 28% ± 14% | |
oligodendrocyte | 8 studies | 27% ± 8% | |
macrophage | 6 studies | 30% ± 8% | |
GABAergic neuron | 6 studies | 40% ± 20% | |
fibroblast | 6 studies | 27% ± 11% | |
interneuron | 5 studies | 37% ± 23% | |
epithelial cell | 5 studies | 33% ± 13% | |
adipocyte | 5 studies | 24% ± 5% | |
type II pneumocyte | 5 studies | 24% ± 6% | |
glutamatergic neuron | 5 studies | 49% ± 25% | |
oligodendrocyte precursor cell | 5 studies | 31% ± 10% | |
club cell | 5 studies | 20% ± 6% | |
smooth muscle cell | 5 studies | 21% ± 3% | |
neuron | 4 studies | 36% ± 19% | |
B cell | 4 studies | 21% ± 4% | |
cardiac muscle cell | 4 studies | 20% ± 2% | |
natural killer cell | 4 studies | 18% ± 2% | |
endothelial cell of lymphatic vessel | 4 studies | 26% ± 7% | |
pericyte | 4 studies | 24% ± 10% | |
basal cell | 4 studies | 26% ± 14% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 18% ± 2% | |
type I pneumocyte | 3 studies | 22% ± 6% | |
CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
lymphocyte | 3 studies | 33% ± 12% | |
goblet cell | 3 studies | 33% ± 20% | |
granule cell | 3 studies | 24% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5968.55 | 1445 / 1445 | 100% | 24.77 | 183 / 183 |
pancreas | 100% | 2921.42 | 328 / 328 | 100% | 42.84 | 178 / 178 |
prostate | 100% | 6912.09 | 245 / 245 | 100% | 66.23 | 502 / 502 |
thymus | 100% | 5385.71 | 653 / 653 | 100% | 58.27 | 605 / 605 |
uterus | 100% | 4512.65 | 170 / 170 | 100% | 35.69 | 459 / 459 |
kidney | 100% | 3958.80 | 89 / 89 | 100% | 41.71 | 900 / 901 |
adrenal gland | 100% | 3559.06 | 258 / 258 | 100% | 46.79 | 229 / 230 |
breast | 100% | 4593.51 | 459 / 459 | 100% | 46.22 | 1113 / 1118 |
bladder | 100% | 6425.43 | 21 / 21 | 99% | 34.26 | 501 / 504 |
brain | 100% | 6346.02 | 2641 / 2642 | 99% | 43.29 | 700 / 705 |
liver | 100% | 2165.34 | 225 / 226 | 100% | 27.24 | 404 / 406 |
skin | 100% | 4524.65 | 1807 / 1809 | 99% | 24.07 | 468 / 472 |
lung | 100% | 4590.67 | 577 / 578 | 99% | 32.90 | 1145 / 1155 |
intestine | 100% | 5935.74 | 966 / 966 | 99% | 27.60 | 521 / 527 |
ovary | 100% | 4119.37 | 180 / 180 | 99% | 25.68 | 425 / 430 |
stomach | 100% | 4161.12 | 359 / 359 | 98% | 23.61 | 281 / 286 |
adipose | 100% | 4324.44 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5107.78 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 45.81 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 38.57 | 29 / 29 |
muscle | 100% | 5650.87 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3764.08 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 31.57 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 29.79 | 1 / 1 |
heart | 99% | 4633.60 | 856 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 88% | 1791.49 | 815 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0031146 | Biological process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
GO_0016055 | Biological process | Wnt signaling pathway |
GO_0030326 | Biological process | embryonic limb morphogenesis |
GO_0019005 | Cellular component | SCF ubiquitin ligase complex |
GO_0000151 | Cellular component | ubiquitin ligase complex |
GO_0005829 | Cellular component | cytosol |
GO_0005515 | Molecular function | protein binding |
Gene name | FBXW4 |
Protein name | F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4) F-box and WD repeat domain containing 4 |
Synonyms | FBW4 SHFM3 |
Description | FUNCTION: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. |
Accessions | P57775 ENST00000664783.1 A0A5F9UQ55 ENST00000331272.9 |