NDRG2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
pericyte	32 studies	34% ± 12%	Explore
fibroblast	21 studies	29% ± 10%	Explore
astrocyte	20 studies	50% ± 19%	Explore
smooth muscle cell	18 studies	33% ± 12%	Explore
conventional dendritic cell	16 studies	25% ± 9%	Explore
endothelial cell	13 studies	28% ± 12%	Explore
oligodendrocyte	13 studies	30% ± 11%	Explore
basal cell	9 studies	36% ± 25%	Explore
capillary endothelial cell	8 studies	18% ± 4%	Explore
epithelial cell	8 studies	36% ± 12%	Explore
myofibroblast cell	8 studies	26% ± 12%	Explore
endothelial cell of lymphatic vessel	7 studies	21% ± 6%	Explore
connective tissue cell	7 studies	25% ± 7%	Explore
ciliated cell	7 studies	25% ± 10%	Explore
club cell	6 studies	25% ± 11%	Explore
respiratory goblet cell	6 studies	29% ± 18%	Explore
secretory cell	6 studies	25% ± 3%	Explore
glial cell	6 studies	32% ± 13%	Explore
oligodendrocyte precursor cell	6 studies	28% ± 12%	Explore
kidney loop of Henle epithelial cell	5 studies	35% ± 11%	Explore
dendritic cell	5 studies	42% ± 17%	Explore
goblet cell	5 studies	21% ± 4%	Explore
duct epithelial cell	4 studies	51% ± 9%	Explore
squamous epithelial cell	4 studies	66% ± 14%	Explore
macrophage	4 studies	22% ± 8%	Explore
ionocyte	3 studies	25% ± 4%	Explore
mononuclear phagocyte	3 studies	27% ± 15%	Explore
glomerular endothelial cell	3 studies	19% ± 3%	Explore
podocyte	3 studies	46% ± 15%	Explore
microglial cell	3 studies	25% ± 4%	Explore
mucus secreting cell	3 studies	52% ± 0%	Explore
Mueller cell	3 studies	61% ± 13%	Explore
endothelial cell of vascular tree	3 studies	27% ± 12%	Explore
neuron	3 studies	31% ± 9%	Explore
intestinal crypt stem cell	3 studies	27% ± 3%	Explore
Schwann cell	3 studies	42% ± 23%	Explore
melanocyte	3 studies	31% ± 11%	Explore
progenitor cell of mammary luminal epithelium	3 studies	63% ± 27%	Explore
hepatocyte	3 studies	47% ± 31%	Explore

Name	Number of supported studies	Average coverage
brain	11 studies	23% ± 8%	Explore
eye	4 studies	18% ± 2%	Explore
lung	4 studies	28% ± 4%	Explore
intestine	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	96378.35	2639 / 2642	100%	661.93	702 / 705
prostate	92%	16585.18	225 / 245	97%	44.53	487 / 502
liver	88%	17731.49	199 / 226	99%	62.55	400 / 406
uterus	99%	29258.58	169 / 170	83%	40.22	382 / 459
breast	93%	21946.33	427 / 459	85%	39.28	951 / 1118
adrenal gland	98%	36647.14	254 / 258	80%	34.07	183 / 230
intestine	86%	14718.54	831 / 966	87%	26.55	459 / 527
ovary	100%	43051.36	180 / 180	60%	21.06	257 / 430
bladder	76%	12765.86	16 / 21	82%	44.66	411 / 504
kidney	58%	8344.03	52 / 89	92%	44.04	832 / 901
esophagus	85%	14008.38	1232 / 1445	59%	14.62	108 / 183
thymus	56%	6877.31	364 / 653	88%	31.93	533 / 605
skin	68%	12178.57	1233 / 1809	58%	19.13	275 / 472
lung	58%	8264.16	334 / 578	66%	19.21	764 / 1155
stomach	39%	6262.97	139 / 359	77%	20.65	219 / 286
pancreas	8%	862.73	25 / 328	95%	40.95	169 / 178
muscle	100%	88265.69	803 / 803	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	39.42	1 / 1
adipose	88%	15386.71	1055 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	87%	39.91	39 / 45
heart	87%	17150.62	745 / 861	0%	0	0 / 0
spleen	85%	14311.05	206 / 241	0%	0	0 / 0
blood vessel	50%	7473.99	673 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	40%	9.96	32 / 80
lymph node	0%	0	0 / 0	10%	1.45	3 / 29
peripheral blood	0%	9.97	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	NDRG2
Protein name	Protein NDRG2 NDRG family member 2 Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Syld709613)
Synonyms	KIAA1248 SYLD
Description	FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. . FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation. .
Accessions	G3V5S0 ENST00000556688.5 G3V271 G3V5P9 ENST00000397853.7 [Q9UN36-1] ENST00000556366.5 ENST00000556420.5 ENST00000557169.5 ENST00000554483.5 ENST00000553784.5 G3V4S2 ENST00000554104.5 G3V3P6 G3V3L1 G3V5A6 ENST00000298687.9 [Q9UN36-1] G3V5B5 G3V4S9 ENST00000403829.7 [Q9UN36-6] ENST00000557616.5 G3V285 ENST00000553593.5 ENST00000554561.5 ENST00000554094.5 G3V239 G3V3P1 ENST00000556561.5 ENST00000555869.5 ENST00000555384.5 G3V5G7 ENST00000557676.5 G3V3X3 H7C0X0 ENST00000553563.5 ENST00000397844.6 [Q9UN36-5] ENST00000555733.5 ENST00000557274.5 G3V578 G3V5D7 ENST00000557149.5 ENST00000397851.6 [Q9UN36-1] G3V420 G3V4T9 ENST00000556008.5 G3V552 G3V5L7 G3V5B7 ENST00000555142.5 ENST00000556974.5 G3V280 ENST00000350792.7 [Q9UN36-2] ENST00000555657.5 A0A0U1RR50 ENST00000554531.5 G3V2S0 ENST00000553442.5 ENST00000556329.6 ENST00000554143.5 [Q9UN36-2] ENST00000556457.5 ENST00000397858.5 [Q9UN36-1] ENST00000553503.5 [Q9UN36-2] ENST00000554489.5 G3V237 G3V2I9 ENST00000554379.5 G3V392 G3V2A6 G3V3D5 G3V4X3 ENST00000557182.5 ENST00000555695.5 ENST00000555026.5 ENST00000554833.5 G3V383 ENST00000555767.5 ENST00000397847.6 [Q9UN36-3] ENST00000554472.5 G3V2T2 ENST00000554419.5 G3V3C3 H0YJT9 ENST00000555158.5 [Q9UN36-2] H0YJ56 ENST00000554893.5 G3V358 ENST00000557264.5 ENST00000556147.6 [Q9UN36-1] ENST00000449431.6 ENST00000557353.5 Q9UN36 ENST00000557633.5 G3V3X2 G3V2Y3 ENST00000298684.9 [Q9UN36-4] G3V5V9 ENST00000556924.5 ENST00000554415.5 ENST00000635386.1 G3V5G0 ENST00000553867.5 ENST00000360463.7 [Q9UN36-2] ENST00000554398.5 G3V5H8

GO_1904706	Biological process	negative regulation of vascular associated smooth muscle cell proliferation
GO_0007165	Biological process	signal transduction
GO_0070373	Biological process	negative regulation of ERK1 and ERK2 cascade
GO_1990874	Biological process	vascular associated smooth muscle cell proliferation
GO_0030154	Biological process	cell differentiation
GO_0010574	Biological process	regulation of vascular endothelial growth factor production
GO_0021762	Biological process	substantia nigra development
GO_0001818	Biological process	negative regulation of cytokine production
GO_0016055	Biological process	Wnt signaling pathway
GO_0090361	Biological process	regulation of platelet-derived growth factor production
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0070062	Cellular component	extracellular exosome
GO_0005794	Cellular component	Golgi apparatus
GO_0005829	Cellular component	cytosol
GO_0030426	Cellular component	growth cone
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function

NDRG2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review