CXXC4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030178Biological processnegative regulation of Wnt signaling pathway
GO_0007352Biological processzygotic specification of dorsal/ventral axis
GO_0016055Biological processWnt signaling pathway
GO_0031410Cellular componentcytoplasmic vesicle
GO_0005737Cellular componentcytoplasm
GO_0030165Molecular functionPDZ domain binding
GO_0008327Molecular functionmethyl-CpG binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameCXXC4
Protein nameCXXC-type zinc finger protein 4 (Inhibition of the Dvl and axin complex protein)
CXXC-type zinc finger protein 4
SynonymsIDAX
DescriptionFUNCTION: Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 (By similarity). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG . .

AccessionsJ9JIF5
Q9H2H0
ENST00000394767.3
A0A8V8TLX0
ENST00000698535.1