APC2 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	13 studies	34% ± 13%	Explore
oligodendrocyte precursor cell	7 studies	25% ± 10%	Explore
neuron	6 studies	30% ± 11%	Explore
glutamatergic neuron	6 studies	36% ± 20%	Explore
interneuron	5 studies	26% ± 14%	Explore
GABAergic neuron	5 studies	33% ± 14%	Explore
amacrine cell	3 studies	21% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	7 studies	29% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	14002.35	2641 / 2642	100%	110.38	703 / 705
adrenal gland	6%	140.56	16 / 258	74%	12.78	171 / 230
skin	0%	0	0 / 1809	68%	2.00	321 / 472
esophagus	0%	1.70	2 / 1445	67%	1.44	123 / 183
eye	0%	0	0 / 0	59%	1.44	47 / 80
stomach	0%	0	0 / 359	48%	0.88	137 / 286
prostate	0%	0	0 / 245	40%	0.58	199 / 502
tonsil	0%	0	0 / 0	38%	0.86	17 / 45
intestine	2%	23.24	15 / 966	33%	0.58	175 / 527
uterus	0%	0	0 / 170	31%	0.70	141 / 459
lung	0%	0	0 / 578	29%	0.51	336 / 1155
kidney	0%	0	0 / 89	28%	0.45	252 / 901
ovary	0%	0	0 / 180	24%	0.38	104 / 430
breast	0%	0	0 / 459	23%	0.37	260 / 1118
liver	0%	0	0 / 226	22%	0.33	89 / 406
bladder	0%	0	0 / 21	17%	0.30	87 / 504
pancreas	0%	0	0 / 328	15%	0.45	27 / 178
lymph node	0%	0	0 / 0	14%	0.18	4 / 29
thymus	0%	0	0 / 653	13%	0.16	76 / 605
blood vessel	0%	1.41	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001708	Biological process	cell fate specification
GO_0090630	Biological process	activation of GTPase activity
GO_0090090	Biological process	negative regulation of canonical Wnt signaling pathway
GO_0007026	Biological process	negative regulation of microtubule depolymerization
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_0016055	Biological process	Wnt signaling pathway
GO_0007399	Biological process	nervous system development
GO_0016477	Biological process	cell migration
GO_0043161	Biological process	proteasome-mediated ubiquitin-dependent protein catabolic process
GO_0007389	Biological process	pattern specification process
GO_0030496	Cellular component	midbody
GO_0031941	Cellular component	filamentous actin
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0098794	Cellular component	postsynapse
GO_0005794	Cellular component	Golgi apparatus
GO_0016342	Cellular component	catenin complex
GO_0030877	Cellular component	beta-catenin destruction complex
GO_0005884	Cellular component	actin filament
GO_0045171	Cellular component	intercellular bridge
GO_0031258	Cellular component	lamellipodium membrane
GO_0005829	Cellular component	cytosol
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005881	Cellular component	cytoplasmic microtubule
GO_0005737	Cellular component	cytoplasm
GO_0008013	Molecular function	beta-catenin binding
GO_0008017	Molecular function	microtubule binding
GO_0045295	Molecular function	gamma-catenin binding
GO_0005515	Molecular function	protein binding

Gene name	APC2
Protein name	Adenomatous polyposis coli protein 2 (Adenomatous polyposis coli protein-like) (APC-like) Adenomatous polyposis coli protein 2 APC2 protein APC regulator of WNT signaling pathway 2
Synonyms	APCL
Description	FUNCTION: Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases . May also function in Wnt signaling by promoting the rapid degradation of CTNNB1 . .
Accessions	ENST00000590877.5 ENST00000590469 Q9UNL8 ENST00000238483.5 K7ERC5 O95996 K7EN62 ENST00000590469.6 [O95996-1] ENST00000587869.5 K7ELQ3 ENST00000587149.6 ENST00000535453.5 [O95996-1] ENST00000233607.6 [O95996-1] A0A0C4DGQ0 B5MDS5

APC2 report