| Name | beta-catenin destruction complex |
| ID | GO_0030877 |
| collection_id | Cellular component |
| Alternative ID | GO:0034742, GO:0034747 |
| Exact synonym | APC-Axin-1-beta-catenin complex, Axin-APC-beta-catenin-GSK3B complex, BDC, beta-catenin degradation complex |
| Description | A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. |
| Comment | Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'. |
| External URL | |
| Genes |