CACYBP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	32 studies	35% ± 16%	Explore
CD8-positive, alpha-beta T cell	32 studies	34% ± 17%	Explore
B cell	31 studies	30% ± 11%	Explore
CD4-positive, alpha-beta T cell	28 studies	38% ± 18%	Explore
macrophage	26 studies	29% ± 13%	Explore
T cell	25 studies	37% ± 14%	Explore
regulatory T cell	24 studies	41% ± 14%	Explore
conventional dendritic cell	23 studies	34% ± 16%	Explore
fibroblast	21 studies	29% ± 16%	Explore
endothelial cell	18 studies	34% ± 13%	Explore
mast cell	16 studies	30% ± 13%	Explore
non-classical monocyte	15 studies	27% ± 11%	Explore
smooth muscle cell	15 studies	25% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	25% ± 5%	Explore
epithelial cell	14 studies	38% ± 20%	Explore
memory B cell	14 studies	27% ± 10%	Explore
mature NK T cell	13 studies	28% ± 10%	Explore
connective tissue cell	13 studies	31% ± 12%	Explore
monocyte	12 studies	32% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	26% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	27% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	26% ± 9%	Explore
pericyte	12 studies	27% ± 10%	Explore
gamma-delta T cell	12 studies	34% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	32% ± 13%	Explore
classical monocyte	11 studies	22% ± 10%	Explore
naive B cell	11 studies	25% ± 11%	Explore
basal cell	11 studies	27% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	34% ± 13%	Explore
mucosal invariant T cell	10 studies	27% ± 6%	Explore
ciliated cell	10 studies	36% ± 14%	Explore
dendritic cell	9 studies	38% ± 21%	Explore
plasmablast	9 studies	43% ± 22%	Explore
plasmacytoid dendritic cell	9 studies	27% ± 9%	Explore
innate lymphoid cell	9 studies	38% ± 16%	Explore
endothelial cell of vascular tree	9 studies	21% ± 3%	Explore
plasma cell	8 studies	36% ± 16%	Explore
leukocyte	8 studies	38% ± 14%	Explore
myofibroblast cell	8 studies	29% ± 13%	Explore
neuron	8 studies	31% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	43% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	29% ± 4%	Explore
epithelial cell of proximal tubule	7 studies	23% ± 9%	Explore
progenitor cell	7 studies	45% ± 14%	Explore
abnormal cell	7 studies	40% ± 17%	Explore
endothelial cell of lymphatic vessel	7 studies	27% ± 10%	Explore
myeloid cell	6 studies	30% ± 12%	Explore
precursor B cell	6 studies	42% ± 19%	Explore
T follicular helper cell	6 studies	31% ± 10%	Explore
hematopoietic precursor cell	5 studies	40% ± 19%	Explore
kidney loop of Henle epithelial cell	5 studies	18% ± 2%	Explore
mesothelial cell	5 studies	33% ± 16%	Explore
vein endothelial cell	5 studies	23% ± 5%	Explore
transit amplifying cell	5 studies	24% ± 4%	Explore
astrocyte	5 studies	23% ± 9%	Explore
erythroblast	5 studies	48% ± 18%	Explore
pro-B cell	5 studies	41% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	47% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	38% ± 12%	Explore
mononuclear phagocyte	4 studies	30% ± 13%	Explore
exhausted T cell	4 studies	37% ± 9%	Explore
enterocyte	4 studies	22% ± 7%	Explore
enteroendocrine cell	4 studies	38% ± 12%	Explore
intestinal crypt stem cell	4 studies	21% ± 6%	Explore
retinal ganglion cell	4 studies	69% ± 23%	Explore
capillary endothelial cell	4 studies	24% ± 7%	Explore
immature B cell	4 studies	34% ± 10%	Explore
type I pneumocyte	4 studies	32% ± 8%	Explore
amacrine cell	4 studies	40% ± 13%	Explore
erythrocyte	4 studies	50% ± 27%	Explore
GABAergic neuron	4 studies	33% ± 10%	Explore
glutamatergic neuron	4 studies	40% ± 16%	Explore
oligodendrocyte precursor cell	4 studies	27% ± 7%	Explore
hematopoietic stem cell	4 studies	27% ± 2%	Explore
oligodendrocyte	4 studies	22% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	23% ± 6%	Explore
precursor cell	3 studies	49% ± 24%	Explore
pancreatic A cell	3 studies	45% ± 4%	Explore
type B pancreatic cell	3 studies	54% ± 9%	Explore
neural crest cell	3 studies	34% ± 10%	Explore
OFF-bipolar cell	3 studies	42% ± 25%	Explore
ON-bipolar cell	3 studies	44% ± 27%	Explore
placental villous trophoblast	3 studies	35% ± 17%	Explore
lymphocyte	3 studies	35% ± 15%	Explore
neuroendocrine cell	3 studies	26% ± 3%	Explore
retina horizontal cell	3 studies	32% ± 8%	Explore
retinal cone cell	3 studies	45% ± 9%	Explore
retinal rod cell	3 studies	32% ± 6%	Explore
adventitial cell	3 studies	20% ± 5%	Explore
alveolar macrophage	3 studies	18% ± 0%	Explore
serous secreting cell	3 studies	20% ± 0%	Explore
intraepithelial lymphocyte	3 studies	33% ± 17%	Explore
Mueller cell	3 studies	26% ± 5%	Explore
germinal center B cell	3 studies	34% ± 14%	Explore
intermediate monocyte	3 studies	35% ± 10%	Explore
CD4-positive helper T cell	3 studies	37% ± 18%	Explore
granulocyte	3 studies	23% ± 4%	Explore
secretory cell	3 studies	28% ± 16%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	52% ± 22%	Explore
group 3 innate lymphoid cell	3 studies	46% ± 20%	Explore
T-helper 17 cell	3 studies	50% ± 25%	Explore
interneuron	3 studies	27% ± 10%	Explore
T-helper 1 cell	3 studies	50% ± 15%	Explore
double negative thymocyte	3 studies	45% ± 28%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	41% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	26% ± 7%	Explore
lung	13 studies	30% ± 12%	Explore
brain	9 studies	26% ± 9%	Explore
intestine	8 studies	29% ± 12%	Explore
kidney	7 studies	33% ± 8%	Explore
eye	7 studies	28% ± 8%	Explore
liver	7 studies	29% ± 18%	Explore
lymph node	6 studies	30% ± 11%	Explore
bone marrow	5 studies	19% ± 4%	Explore
uterus	4 studies	27% ± 14%	Explore
pancreas	3 studies	46% ± 3%	Explore
adrenal gland	3 studies	38% ± 17%	Explore
skin	3 studies	21% ± 4%	Explore
thymus	3 studies	51% ± 22%	Explore
breast	3 studies	23% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	2532.21	459 / 459	100%	74.94	1118 / 1118
ovary	100%	3908.81	180 / 180	100%	61.04	430 / 430
esophagus	100%	2566.76	1444 / 1445	100%	49.63	183 / 183
brain	100%	6108.80	2640 / 2642	100%	59.69	705 / 705
bladder	100%	3335.76	21 / 21	100%	63.81	503 / 504
stomach	100%	2094.23	359 / 359	100%	56.17	285 / 286
intestine	100%	2777.64	966 / 966	99%	56.94	524 / 527
uterus	99%	2743.62	169 / 170	100%	78.73	459 / 459
lung	98%	2775.70	569 / 578	100%	61.16	1155 / 1155
prostate	99%	1885.36	243 / 245	99%	34.44	498 / 502
skin	99%	2884.37	1798 / 1809	99%	60.33	466 / 472
thymus	99%	1961.98	645 / 653	99%	35.40	600 / 605
adrenal gland	99%	2755.50	256 / 258	98%	41.78	226 / 230
kidney	100%	2578.42	89 / 89	97%	31.45	872 / 901
pancreas	95%	1199.58	310 / 328	99%	39.70	176 / 178
liver	94%	1414.09	212 / 226	97%	36.88	394 / 406
lymph node	0%	0	0 / 0	100%	77.71	29 / 29
spleen	100%	2604.20	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	63.36	45 / 45
ureter	0%	0	0 / 0	100%	37.46	1 / 1
adipose	100%	2908.93	1202 / 1204	0%	0	0 / 0
blood vessel	100%	2694.15	1331 / 1335	0%	0	0 / 0
muscle	99%	2460.42	798 / 803	0%	0	0 / 0
heart	94%	2049.79	806 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	24.58	72 / 80
peripheral blood	87%	2995.15	804 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1990830	Biological process	cellular response to leukemia inhibitory factor
GO_0007507	Biological process	heart development
GO_0019005	Cellular component	SCF ubiquitin ligase complex
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005641	Cellular component	nuclear envelope lumen
GO_0030877	Cellular component	beta-catenin destruction complex
GO_0005634	Cellular component	nucleus
GO_0042803	Molecular function	protein homodimerization activity
GO_0044548	Molecular function	S100 protein binding
GO_0019904	Molecular function	protein domain specific binding
GO_0031625	Molecular function	ubiquitin protein ligase binding
GO_0005515	Molecular function	protein binding
GO_0015631	Molecular function	tubulin binding

IV. Literature review

[source]

Gene name	CACYBP
Protein name	Calcyclin-binding protein (CacyBP) (hCacyBP) (S100A6-binding protein) (Siah-interacting protein) Calcyclin-binding protein Calcyclin binding protein
Synonyms	PNAS-107 SIP S100A6BP
Description	FUNCTION: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). . FUNCTION: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). .
Accessions	ENST00000406752.1 [Q9HB71-2] ENST00000405362.1 [Q9HB71-3] B2ZWH1 ENST00000426793.1 Q9HB71 ENST00000613570.4 [Q9HB71-3] Q6NVY0 ENST00000367679.7 [Q9HB71-1]

CACYBP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review